Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis

Table 2 Sensitivity analyses

Strata of analysis for each outcome	Number of studies included	HR (95% CI); P-value	Heterogeneity
A. Studies with definition for cancer specific mortality included [6, 9, 19, 20, 51, 52, 54, 55, 58, 60]	10	1.49 (1.29 to 1.72); P <0.001	I²:23.4%; P = 0.23
B. Only Stage III/IV colorectal carcinoma studies included [6, 24, 51, 52]	High versus Low: 2	High versus Low: 1.64 (1.34 to 2.00); P <0.001	I²: 0%; P = 0.38
	Positive versus Negative: 2	Positive versus Negative: 1.95 (1.32 to 2.87); P = 0.001	I²: 46.7%; P = 0.17
	Overall colorectal studies: 4	Overall colorectal studies: 1.70 (1.42 to 2.03); P <0.001	I²: 7.2%; P = 0.36

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