Skip to main content

Table 1 Serum biological indicators and bone-mineral density between rats on the normal-calcium diet and rats on thelow-calcium diet.

From: Calcium-deficiency assessment and biomarker identification by an integrated urinary metabonomics analysis

  Normal-calcium group Low-calcium group
  Week 4 Week 8 Week12 Week 4 Week 8 Week 12
Calcium, mmol/l 2.53 ± 0.26 2.55 ± 0.19 2.56 ± 0.28 2.55 ± 0.23 2.51 ± 0.17 2.31 ± 0.28*
Phosphorus, mg/l 9.38 ± 1.94 9.29 ± 2.35 9.17 ± 2.11 9.29 ± 2.03 8.85 ± 1.60 8.67 ± 2.03
AP, U/l 85.8 ± 21.0 82.4 ± 14.2 80.1 ± 16.3 96.6 ± 17.9 111.7 ± 20.3* 117.8 ± 17.9*
PTH, pg/ml 45.6 ± 6.08 42.3 ± 2.22 31.2 ± 1.75 59.4 ± 6.87* 53.7 ± 1.95* 42.8 ± 2.13*
1,25, OH2D3, pg/ml 70.7 ± 14.9 71.6 ± 18.1 72.2 ± 19.9 87.2 ± 23.1* 120.2 ± 26.4* 121.3 ± 19.1*
FGF23, pg/ml - - 211 ± 9.28 - - 234 ± 14.44*
BMD, g/cm2 0.258 ± 0.02 0.285 ± 0.02 0.298 ± 0.02 0.254 ± 0.03 0.277 ± 0.01 0.262 ± 0.03*
  1. Abbreviations: AP, alkaline phosphatase; BMD, bone-mineral density; FGF23, fibroblast growth factor 23; LCG, low-calcium group; NCG, normal-calcium group, PTH, parathyroid hormone. *Significant differences (P<0.05) for mean values of LCG compared with NCG at the same time points.