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Table 1 Patient characteristics
| Characteristic | BD + HDM/SCT (number = 28) | HDM/SCT (number = 28) | Pvalue |
|---|---|---|---|
| Age (years) | |||
| Median | 53 | 51.5 | 0.23 |
| Range | 38-65 | 37-63 | |
| Male/female (number) | 18/10 | 16/12 | 0.78 |
| Organ involvement, number (%) | |||
| Kidney | 28 (100) | 28 (100) | 1.0 |
| Heart | 17 (60.7) | 15 (53.5) | 0.79 |
| Liver | 1 (3.6) | 3 (10.7) | 0.61 |
| Nervous system | 3 (10.7) | 2 (7.1) | 1.0 |
| >1 organ involved | 17 (60.7) | 16 (57.1) | 1.0 |
| Cardiac stage, number (%)a | |||
| I | 14 (50) | 12 (42.9) | 0.86 |
| II | 10 (35.7) | 11 (39.3) | |
| III | 4 (14.3) | 5 (17.8) | |
| Involved FLC, number (%) | |||
| κ | 3 (10.7) | 2 (7.1) | 1.0 |
| λ | 25 (89.3) | 26 (92.9) | |
| Abnormal FLC κ-to-λ ratio number (%) | 26 (92.9) | 27 (96.4) | 1.0 |
| ECOG PS (0/1/2), number (%) | |||
| 0 | 13 (44.4) | 14 (46.2) | 0.75 |
| 1 | 10 (37) | 11 (42.3) | |
| 2 | 5 (18.6) | 3 (11.5) | |
| 24-hour urine protein (g/24 hour) | 4.6 ± 2.2 | 5.8 ± 4.1 | 0.18 |
| Albumin (g/L) | 26.8 ± 6.1 | 25.7 ± 4.9 | 0.44 |
| Creatinine (mg/dL) | 0.8 ± 0.3 | 0.8 ± 0.4 | 0.72 |
| GFR (mL/min) | 89.0 ± 19.6 | 85.1 ± 25.6 | 0.53 |
| Marrow plasma cells (%) | 3.2 ± 2.7 | 2.8 ± 2.1 | 0.59 |
| Echocardiogram septal thickness (mm) | 11.7 ± 2.4 | 11.1 ± 1.8 | 0.33 |
| Ejection fraction (%) | 60.8 ± 6.5 | 62.7 ± 6.1 | 0.27 |
| Alkaline phosphatasea (U/L) | |||
| Median | 58 | 49 | 0.11 |
| Range | 23 to 321 | 33 to 661 | |
| NT-proBNP (ng/L) | |||
| Median | 268 | 249 | 0.32 |
| Range | 55.5 to 13,730 | 15.2 to 7,709 | |
| >8500 ng/L (%) | 1 (3.6) | 1 (3.6) | |
| BNP (ng/L) | |||
| Median | 117 | 120 | 0.85 |
| Range | 22 to 3,261 | 17 to 3,078 | |
| Troponin-I (ng/ml) | |||
| Median | 0.003 | 0.003 | 0.83 |
| Range | 0 to 0.15 | 0 to 0.12 | |
| iFLC (mg/L) | |||
| Median | 114.9 | 97.8 | 0.15 |
| Range | 25 to 516 | 24 to 204 | |
| dFLC (mg/L) | |||
| Median | 96.1 | 64.8 | 0,12 |
| Range | 14 to 471 | 14 to 163 | |
| >180 mg/L (%) | 2 (7.1) | 0 |
