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Figure 4 | BMC Medicine

Figure 4

From: Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model

Figure 4

Protein localization of KCNJ10 in the cochlea of Slc26a4 +/+ and Slc26a4 -/- mice. a: Overview of cochlea; bar = 100 μm. Compare to Fig. 1a to note the enlarged scala media and the distended Reissner's membrane. b-c: Detail of lateral wall and spiral ganglia (insert); main bar: 10 μm, insert: 5 μm. Expression of KCNJ10 in Slc26a4 -/- mice was absent in stria vascularis but unchanged in spiral ganglion cells. RM, Reissner's membrane, SV, stria vascularis; SP, spiral prominence; SL, spiral ligament; LIM, spiral limbus; SG, spiral ganglion.

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