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Table 1 Relative luciferase activity of extracts from control and THC treated cells. NIH 3T3 cells co-transfected with MHV 68 ORF 50 plus CMV control (top rows of the table). BCBL-1 cells were co-transfected with the KSHV ORF 50 plus CMV control (bottom rows of the table). Data represent averages from three independent co-transfection experiments.

From: Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro

Treatment of NIH 3T3 cells MHV 68 ORF 50 promoter (firefly luciferase) CMV renilla luciferase
DMSO 100% +/- 14% 100% +/- 11%
5 μg/ml THC 13.5% +/- 1.5% 65.8% +/- 9%
Treatment of BCBL-1 cells KSHV ORF 50 (firefly luciferase) CMV renilla luciferase
DMSO 100% +/- 14% 100% +/- 3%
5 μg/ml THC 28% +/- 13% 128% +/- 3%