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Table 4 Histopathology

From: Hyper-IgG4 disease: report and characterisation of a new disease

Patient no., sex, age Organ Fibrosis* Lymphoplasmacytic infiltrate† Lymphoid follicles Venulitis Eosinophilic component IgG4-positive plasma cells‡
(1) Male, 52 Kidney +++ +++ Yes No No 3
  Liver ++ + No No Yes 0
(2) Male, 73 Retroperitoneum +++ +++ Yes Yes Yes 3
(3) Male, 39 Omentum + ++ Yes No No 3
(4) Male, 53 Retroperitoneum +++ +++ Yes Yes Yes 3
(5) Male, 45 Periureter +++ +++ Yes Yes No 2
(6) Female, 58 Retroperitoneum +++ +++ No Yes No 3
(7) Female, 55 Para-aortic tissue +++ +++ Yes Yes No 3
(8) Male, 47 Periureter tissue +++ + Yes Yes No 2
(9) Male, 48 Retroperitoneum +++ ++ No No No 2
(10) Male, 73 Retroperitoneum +++ +++ Yes Yes Yes 1
(11) Female, 56 Retroperitoneum +++ ++ Yes No No 1
(12) Male, 53 Liver ++ + No No No 1
  Colon ++ + No No No 0
  1. *Degree of interstitial fibrosis: +, mild; ++, moderate; +++, severe fibrosis.
  2. †Degree of inflammation: +++ (severe), >100 inflammatory cells/HPF; ++ (moderate), 30–100 cells/HPF; + (mild), 10–30 cells/HPF
  3. ‡IgG4-positive plasma cells: 0, no IgG4 plasma cells/high power field (HPF); 1, ≤ 20 cells/HPF), 2, 20–50 cells/HPF; 3, ≥ 50 cells/HPF (criteria of Aoki et al [12]).