Table 2 Blood pressure, heart rate and lipid levels in different genotypes of the β2-adrenergic receptor polymorphisms.
n | SBP mmHg | DBP mmHg | HR beats/min | n | Cholesterol mg/dl | Triglycerides mg/dl | n | HDL mg/dL | LDL mg/dL | |
|---|---|---|---|---|---|---|---|---|---|---|
All | 429 | 130.5 ± 15.7 | 79.6 ± 9.2 | 76.8 ± 9.5 | 360 | 224.7 ± 39.4 | 171.5 ± 95.7 | 278 | 46.8 ± 14.3 | 146.6 ± 35.9 |
Codon -47 | ||||||||||
Cys/Cys | 131 | 130 ± 1 ± 16.3 | 79.8 ± 9.4 | 77.0 ± 9.1 | 112 | 226.0 ± 40.3 | 168.6 ± 76.5 | 93 | 46.0 ± 14.3 | 148.9 ± 32.9 |
Cys/Arg | 195 | 130.9 ± 15.6 | 79.6 ± 9.3 | 76.6 ± 8.9 | 163 | 222.5 ± 38.5 | 175.3 ± 102.5 | 123 | 47.3 ± 13.9 | 144.0 ± 38.6 |
Arg/Arg | 103 | 130.1 ± 15.1 | 79.4 ± 8.7 | 76.9 ± 11.0 | 85 | 227.6 ± 40.1 | 167.9 ± 105.2 | 62 | 46.9 ± 15.5 | 148.3 ± 35.1 |
P | 0.878 | 0.942 | 0.924 | 0.594 | 0.789 | 0.796 | 0.578 | |||
Codon 16 | ||||||||||
Arg/Arg | 59 | 133.6 ± 17.2 | 80.9 ± 9.3 | 78.4 ± 9.3 | 53 | 228.2 ± 45.7 | 178.5 ± 114.2 | 39 | 49.7 ± 15.9 | 149.5 ± 34.8 |
Arg/Gly | 197 | 130.0 ± 15.9 | 79.8 ± 9.5 | 76.6 ± 9.4 | 158 | 221.4 ± 38.6 | 164.7 ± 92.5 | 123 | 47.0 ± 14.4 | 143 ± 37.2 |
Gly/Gly | 173 | 129.9 ± 14.9 | 79.0 ± 8.9 | 76.5 ± 9.7 | 149 | 227.2 ± 37.8 | 176.0 ± 91.8 | 116 | 45.7 ± 13.8 | 149.4 ± 34.9 |
P | 0.268 | 0.389 | 0.371 | 0.345 | 0.496 | 0.305 | 0.348 | |||
Codon 27 | ||||||||||
Gln/Gln | 109 | 130.7 ± 14.5 | 80.2 ± 9.0 | 77.2 ± 9.2 | 93 | 222.7 ± 42.3 | 175.9 ± 89.4 | 74 | 44.9 ± 14.0 | 145.6 ± 32.9 |
Gln/Glu | 202 | 130.8 ± 15.2 | 79.2 ± 9.1 | 76.6 ± 9.2 | 164 | 225.3 ± 38.3 | 174.1 ± 100.9 | 128 | 47.2 ± 14.3 | 146.5 ± 38.2 |
Glu/Glu | 118 | 130.5 ± 15.7 | 79.9 ± 9.5 | 76.8 ± 10.2 | 103 | 224.8 ± 39.4 | 163.3 ± 93.0 | 76 | 48.0 ± 14.8 | 147.8 ± 35.2 |
P | 0.840 | 0.592 | 0.859 | 0.841 | 0.585 | 0.395 | 0.930 |