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Table 3 Top SNPs ranked by univariate analysis for trial S9321

From: Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival

Rank rs ID pval Gene Sym Gene Name SNP Function
1.0 rs2066534 0.001280 FMO3 Flavin containing monooxygenase 3 intron
2.0 rs696217 0.001877 GHRL Ghrelin precursor coding-nonsynon
3.0 rs1043424 0.002404 PINK1 PTEN induced putative Kinase 1 coding-nonsynon
4.0 rs174680 0.003361 COMT Catechol-O-methyltransferase intron
5.0 rs316132 0.003443 GSTA4 Glutathione S-transferase A4 intron, TagSNP:GSTA4
6.0 rs1884725 0.004564 XDH Xanthine dehydrogenase coding-nonsynon
7.0 rs2069391 0.004830 CDK2 Cyclin-dependent kinase 2  
8.0 rs4148217 0.006167 ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) coding-nonsynon
9.0 rs11700112 0.007423 PAK7 P21 (CDKN1A)-activated kinase 7 coding-nonsynon
10.0 rs1052536 0.007643 LIG3 Ligase III, DNA, ATP-dependent untranslated
11.0 rs2618346 0.008033 DUSP1 Dual specificity phosphatase 1 3' UTR
12.0 rs9282564 0.008239 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 coding-nonsynon
13.0 rs53683 0.008429 GHRL Ghrelin precursor intron
14.0 rs2227314 0.009244 IL12A Interleukin 12A (natural killer cell stimulatory factor 1, cytotixic lymphocyte maturation factor 1, p35) intron
15.0 rs1801243 0.010739 ATP7B ATPase, Cu++ transporting, beta polypeptide (Wilson disease) coding-nonsynon
16.0 rs2953983 0.010792 POLB Polymerase (DNA directed), beta intron
17.0 rs4148946 0.011822 CHST3 Sarbohydrate (chondroitin 6) sulfotransferase 3 untranslated
18.0 rs7185307 0.011895 TNFRSF17 Tumor necrosis factor receptor superfamily, member 17 locus, TagSNP:TNFRSG17(BCMA)
19.0 rs699473 0.012077 SOD3 Superoxide dismutase 2, extracellular intron
20.0 rs880324 0.012969 NFATC2 Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 intron