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Table 3 DNMT3A -448A>G genotype and allele frequencies in control subjects

From: A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma

Groups

Genotype

  

Allele

 
 

GG (%)

AG (%)

AA (%)

A (%)

P *

Total

218 (63.0)

118 (34.1)

10 (2.9)

19.9

 

Age years)

    

0.09†

≤60

80 (23.1)

57 (16.5)

4 (1.2)

9.4

 

>60

138 (39.9)

61 (17.6)

6 (1.7)

10.5

 

Gender

    

0.521‡

Male

152 (43.9)

82 (23.7)

9 (2.6)

14.5

 

Female

66 (19.1)

36 (10.4)

1 (0.3)

5.5

 
  1. *Chi-squared test.
  2. † The frequency of A allele in individuals at ≤ 60 years versus > 60 years.
  3. ‡ The frequency of A allele in individuals in male versus female.
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BMC Medicine

ISSN: 1741-7015

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