Table 7 Distribution of -448A>G DNMT3A genotypes and associated odds ratio (OR) in relation to age and gender in oesophagus carcinoma (EC) cases
Genotype | EC cases (%) | Controls (%) | OR | Pvalue |
|---|---|---|---|---|
Age(years) | Â | Â | Â | Â |
≤60 |  |  |  |  |
GG | 43 (44.8) | 80 (33.2) | 1.0 | Â |
AG | 15 (15.6) | 57 (23.7) | 0.490 (0.248-0.965) | 0.037 |
AA | 3 (3.1) | 4 (1.7) | 1.395 (0.298-6.523) | 0.985 |
>60 | Â | Â | Â | Â |
GG | 18 (18.7) | 69 (28.6) | 1.0 | Â |
AG | 13 (13.5) | 29 (12.0) | 1.718 (0.746-3.960) | 0.201 |
AA | 4 (4.2) | 2 (0.8) | 7.667(1.300-45.230) | 0.026 |
Gender | Â | Â | Â | Â |
Male | Â | Â | Â | Â |
GG | 46 (47.9) | 96(39.8) | 1.0 | Â |
AG | 20 (20.8) | 59 (24.5) | 0.707 (0.382-1.311) | 0.271 |
AA | 5 (5.2) | 5 (2.1) | 2.087 (0.575-7.570) | 0.428 |
Female | Â | Â | Â | Â |
GG | 15 (15.6) | 53(22.0) | 1.0 | Â |
AG | 8 (8.3) | 27 (11.2) | 1.047 (0.395-2.776) | 0.927 |
AA | 2 (2.1) | 1 (0.4) | 7.067 (0.599-83.374) | 0.140 |