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Table 3 Proteins found unique to the Caucasian-American dataset that are reported to be involved in breast cancer, as annotated by Ingenuity Systems or BIOBASE.

From: The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo

Symbol Entrez gene name Location Entrez gene ID
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 Plasma membrane 10057
ACE Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Plasma membrane 1636
BCAR3 Breast cancer anti-estrogen resistance 3 Cytoplasm 8412
CDON Cdon homolog (mouse) Plasma membrane 50937
CLCA2 CLCA family member 2, chloride channel regulator Plasma membrane 9635
CSF1R Colony stimulating factor 1 receptor Plasma membrane 1436
CTGF Connective tissue growth factor Extracellular space 1490
DAPK1 Death-associated protein kinase 1 Cytoplasm 1612
DLG5 Discs, large homolog 5 (Drosophila) Plasma membrane 9231
ERBB3 V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) Plasma membrane 2065
FRZB Frizzled-related protein Extracellular space 2487
GREB1 GREB1 protein Cytoplasm 9687
HGF Hepatocyte growth factor (hepapoietin A; scatter factor) Extracellular space 3082
HPN Hepsin (transmembrane protease, serine 1) Plasma membrane 3249
HSPA8 Heat shock 70 kDa protein 8 Cytoplasm 3312
IL17RB Interleukin 17 receptor B Plasma membrane 55540
IRS2 Insulin receptor substrate 2 Cytoplasm 8660
ITGA6 Integrin, alpha 6 Plasma membrane 3655
KCNH1 Potassium voltage-gated channel, subfamily H (eag-related), member 1 Plasma membrane 3756
KISS1 KiSS-1 metastasis-suppressor Cytoplasm 3814
LGALS3 Lectin, galactoside-binding, soluble, 3 Extracellular space 3958
LPA Lipoprotein, Lp(a) Extracellular space 4018
LPHN2 Latrophilin 2 Plasma membrane 23266
LTA Lymphotoxin alpha (TNF superfamily, member 1) Extracellular space 4049
MAP2K5 Mitogen-activated protein kinase kinase 5 Cytoplasm 5607
MINK1 Misshapen-like kinase 1 (zebrafish) Cytoplasm 50488
NOS3 Nitric oxide synthase 3 (endothelial cell) Cytoplasm 4846
NOTCH4 Notch homolog 4 (Drosophila) Plasma membrane 4855
NRG1 Neuregulin 1 Extracellular space 3084
OAS3 2'-5'-oligoadenylate synthetase 3, 100 kDa Cytoplasm 4940
P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide Cytoplasm 5034
PKD1 Polycystic kidney disease 1 (autosomal dominant) Plasma membrane 5310
PLG Plasminogen Extracellular space 5340
PTPRF Protein tyrosine phosphatase, receptor type, F Plasma membrane 5792
RASA1 RAS p21 protein activator (GTPase activating protein) 1 Cytoplasm 5921
SERPINI2 Serpin peptidase inhibitor, clade I (pancpin), member 2 Extracellular space 5276
SH3RF1 SH3 domain containing ring finger 1 Cytoplasm 57630
SOCS1 Suppressor of cytokine signaling 1 Cytoplasm 8651
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) Plasma membrane 23158
TGFBR2 Transforming growth factor, beta receptor II (70/80 kDa) Plasma membrane 7048
TIAM1 T-cell lymphoma invasion and metastasis 1 Cytoplasm 7074
TNN Tenascin N Plasma membrane 63923
TPI1 Triosephosphate isomerase 1 Cytoplasm 7167
VWF von Willebrand factor Extracellular space 7450
WISP2 WNT1 inducible signaling pathway protein 2 Extracellular space 8839
WNT11 Wingless-type MMTV integration site family, member 11 Extracellular space 7481
YWHAZ Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide Cytoplasm 7534