Study Pop | N | Endpoints | Thresholds | Odds ratio or Hazard Ratio | Ref |
---|---|---|---|---|---|
GUSTOIV (NSTEACS) | 2,081 + 429 | Death (one year) | Tertiles < 1,200 ng/L, 1,200 to 1,800 ng/L > 1,800 ng/L | 1.5%, 5%, 14.1% | [46] |
FRISC-II (invasive vs conservative) | 2,079 | Death or MI (2 yrs) | Invasive at > 1,800 ng/L Invasive 1,200 to 1,800 ng/L Invasive < 1,200 or Trop -ve | HR 0.49 (risk reduction) HR 0.68 No benefit | [47] |
ASSENT-2/plus (STEMI) | 741 | Death (1 yr) | Tertiles < 1,200, 1,200 to 1,800, > 1,800 | 2.1%, 5.0%, 14% | [48] |
AMI | 1,142 | Death or HF (1.5 yr) | <1,470 ng/L, >1,470 ng/L | HR 1.77 | [49] |