Figure 7
From: The VHL-dependent regulation of microRNAs in renal cancer
CAIX and miR-210 expression in tumours with and without VHL mutation and VHL promoter methylation. Measurements of CAIX mRNA and miR-210 expression were determined by qPCR and normalised to β-actin mRNA expression and an average of RNU43 and RNU48 expression, respectively. qPCR for each sample was performed in triplicate. Expression of CAIX and miR-210 was found to be increased in tumours with VHL mutation or promoter methylation compared to tumours in which neither was identified (P = 0.045 and 0.011, respectively).