Table 2 Characteristics of included trials: Short-term trialsa
Trial | Clinical problem | Sample size (% dropout) | Concealment | Outcome used for meta-analysis | Intervention details | Standard basic care in all groups | |
|---|---|---|---|---|---|---|---|
Cabrini et al. [41] | Bronchoscopy | 48 (0) | Unclear | VAS discomfort after bronchoscopy | N:1 D:20 T:- | Ac:C CA S:I C 1 | Lidocaine as needed |
Dundee et al. [43] | Perioperative nausea (minor gynecologic operations) | 75 (0) | Unclear | Number of patients vomiting | N:1 D:5 T:- | Ac:C CA S:I C 1 | Premedication 10 mg nalbophine |
Fanti et al. [45] | Colonoscopy | 30 (0) | Unclear | Satisfaction with sedation using a verbal rating scale | N:1 D:4 T:- | Ac:C EA S:I C 1 | Midazolam 0.02 mg/kg before and during colonoscopyb |
Gioia et al. [48] | Sedation during cataract surgery | 75 (0) | Unclear | Postoperative anxiety evaluation (VAS) | N:1 D:60 T:- | Ac:C CA S:I C 1 | Topical eye anesthesia (lidocaine 4%) |
Karst et al. [50] | Anxiety and tooth extraction | 48 (0) | Unclear | VAS anxiety | N:1 D:25 T:- | Ac:C EarA S:II C 1 | Local anesthesia (articaine hydrochloride) |
Li et al. [55] | Colonoscopy | 36 (0) | Unclear | VAS pain intensity | N:1 D:30 T:- | Ac:C EA S:I C 1 | Routine analgesia and sedation as needed |
Rusy et al. [62] | Postoperative nausea after tonsillectomy | 120 (0) | Unclear | Incidence of nausea, vomiting, rescue therapy in first 24 hours | N:1 D:20 T:- | Ac:C EA S:I C 2 | Standardized anesthesia, analgesia as needed |
Ziaei & Hayipour [69] | Pain reduction and relaxation during labor | 90 (unclear) | Unclear | VAS pain after 2 hours | N:1 D:n.i.. T:- | Ac:C CA S:I C 1 | Unclear |