Table 1 Approved anticancer drugs using nanocarriersa
Trade name/compound | Manufacturer | Nanocarrier |
|---|---|---|
Abraxane/paclitaxel | Abraxis Biosciences | Albumin-bound paclitaxel |
Bexxar/anti-CD20 conjugated to iodine-131 | Corixa/GlaxoSmithKline | Radioimmunoconjugate |
DaunoXome/daunorubicin | Diatos (available in France) | Liposome |
Doxil/Caelyx/doxorubicin | Ortho Biotech | Liposome |
Myoset/doxorubicin | Cephalon (available in Europe) | Nonpegylated liposome |
Oncaspar/PEG-L-asparaginase | Enzon | Polymer-protein conjugate |
Ontak/IL-2 fused to diphtheria toxin | Eisai Inc | Immunotoxic fusion protein |
SMANCS/zinostatin | Yamanouchi Pharma | Polymer-protein conjugate |
Zevalin/anti-CD20 conjugated to yttrium-90 | Cell Therapeutics Inc. | Radioimmunoconjugate |
Zoladex/goserelin acetate | AstraZeneca | Polymer rods |