| Dataset (years) | |||||
---|---|---|---|---|---|---|
Immune-mediated disease (ICD code3) | ORLS1 (1963 to 1998) | ORLS2 (1999 to 2008) | England (1999 to 2008) | |||
 | O | E | O | E | O | E |
Addison's disease (255.4) | 13 | 8.7 | 12 | 4.1 | 205 | 95.9 |
Ankylosing spondylitis (720) | 18 | 13.4 | 10 | 8.5 | 373 | 194.7 |
Autoimmune haemolytic anaemia (283) | 16 | 5.7 | 17 | 4.7 | 353 | 93.4 |
Chronic active hepatitis (571.4) | 15 | 6.7 | 6 | 1.5 | 93 | 45.7 |
Coeliac disease (579.0) | 27 | 20.0 | 24 | 17.8 | 474 | 392.0 |
Dermatomyositis, polymyositis (710.3,710.4) | 11 | 5.6 | 7 | 2.4 | 167 | 55.2 |
Diabetes mellitus under 30 (250) | 23 | 11.2 | 18 | 6.7 | 224 | 96.9 |
Goodpasture's syndrome (466.2) | 2 | 0.9 | 4 | 0.6 | 24 | 8.6 |
Hashimoto's thyroiditis (245) | 8 | 9.0 | 3 | 3.3 | 100 | 70.9 |
Idiopathic thrombocytopenia purpura (287.3) | 9 | 4.4 | 21 | 13.4 | 465 | 225.0 |
Multiple sclerosis (340) | 106 | 48.2 | 88 | 36.6 | 1509 | 728.8 |
Myasthenia gravis (358) | 13 | 6.4 | 13 | 5.6 | 282 | 125.9 |
Myxoedema (244) | 202 | 139.8 | 431 | 342.2 | 11104 | 9284.7 |
Pemphigus, pemphigoid (694.4,694.5) | 38 | 14.2 | 23 | 7.1 | 375 | 170.8 |
Pernicious anaemia (281) | 120 | 100.5 | 30 | 21.0 | 1012 | 754.2 |
Polyarteritis nodosa (446) | 18 | 6.3 | 3 | 0.7 | 73 | 20.7 |
Primary biliary cirrhosis (571.6) | 7 | 5.4 | 11 | 4.0 | 150 | 101.2 |
Psoriasis (696.0,696.1,696.8,696.9) | 99 | 61.7 | 53 | 32.8 | 1318 | 812.5 |
Rheumatoid arthritis (714) | 450 | 322.1 | 281 | 192.9 | 6825 | 4352.5 |
Scleroderma (710.1) | 9 | 4.2 | 9 | 5.9 | 244 | 124.8 |
Sjogren's syndrome (710.2) | 10 | 3.5 | 13 | 6.8 | 305 | 152.2 |
Systemic lupus erythematosus (710.0) | 26 | 7.2 | 35 | 7.8 | 636 | 174.8 |
Thyrotoxicosis (242) | 134 | 117.8 | 83 | 54.7 | 1429 | 1081.7 |