Table 1 SEPT9 detection in specimens collected prospectively from colonoscopy patients
From: Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer
| Â | All Evaluable Subjects (age 24-86 years) | Asymptomatic Subjects (age 50-75 years) | ||
|---|---|---|---|---|
| Â | Total | SEPT9+ | Total | SEPT9+ |
Total subjects | 300 | 21 | 195 | 15 |
Colorectal cancer | 0 | 0 | 0 | 0 |
Other cancer (carcinoid tumor) | 1 | 0 | 0 | 0 |
Adenoma | 104 | 12 | 78 | 8 |
   Adenoma ≤ 10 mm | 93 | 11 | 69 | 7 |
   Adenoma > 10 mm | 11 | 1 | 9 | 1 |
Hyperplastic/other polyp | 38 | 1 | 27 | 1 |
Diverticulosis | 43 | 4 | 27 | 3 |
Hemorrhoids | 29 | 1 | 12 | 0 |
Crohn's disease/colitis | 7 | 0 | 3 | 0 |
Other colonic findings | 21 | 0 | 9 | 0 |
Unsatisfactory prep/aborted | 11 | 0 | 9 | 0 |
Normal | 53 | 3 | 34 | 3 |