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Table 1 Characteristics of included studies

From: The Alvarado score for predicting acute appendicitis: a systematic review

First author, study year [reference] Number of patients Age
(years)
Gender
n
Appendicitis prevalence (%) Country Setting Study type Patient population
Abdeldaim 2007 [19] 242 Median 42
Range 8 to 76
Male 90
Female 152
51 Ireland Emergency department Retrospective Right iliac fossa pain
Al Qahtani 2004 [8] 211 Mean 32
Range 13 to 70
Male 125
Female 86
57 Saudi Arabia Emergency department Prospective Suspected acute appendicitis
Alvarado 1986 [5] 277 Mean 25.3
Range 4 to 80
Male 131
Female 96
82 USA Hospital inpatients Prospective Abdominal pain
Arain 2001 [20] 100 Mean 19.9 Males 44
Females 56
48 Pakistan Surgical unit Prospective Suspected acute appendicitis
Baidya 2007 [44] 231 Mean 26.3
Range 16 to 65
Male 141
Female 90
52 India Emergency department Prospective Right iliac fossa pain
Bond 1990 [21] 187 Range 0 to 18   61 USA Emergency department Prospective Abdominal pain
Borges 2003 [22] 76 Age 2 to 6 = 23 Age 7 to 10 = 38 Age > 10 = 15 Male 40
Female 36
71 Brazil Emergency department Prospective Suspected acute appendicitis
Canavosso 2008 [23] 224 Mean 26.65
Range 13 to 82
Male 117
Female 10
84 Argentina Emergency department Prospective Right lower quadrant pain
Chan 2001 [25] 148 Mean 29
Range 10 to 73
Male 107
Female 41
34 Singapore Emergency department Retrospective Suspected acute appendicitis
Chan 2003 [24] 175 Mean 30
Range 8 to 73
Male 130
Female 45
43 Singapore Emergency department Prospective Right iliac fossa pain
Denizbasi 2003 [45] 221 Mean 26.6 Male 112
Female 109
79 Turkey Emergency department Prospective Abdominal pain and suspected acute appendicitis
Escriba 2011 [42] 99 Mean 11.2
Range 4 to 17.8
Male 62
Female 37
42 Spain Emergency department Prospective Abdominal pain/suspected appendicitis
Farahnak 2007 [26] 21 - - 48 Iran Emergency department Prospective Abdominal pain
Gwynn 2001 [27] 215 - - 66 USA Emergency department Retrospective Abdominal pain
Hsiao 2005 [28] 222 Mean 9.4
Range 1 to 13
Male 146
Female 76
50 Taiwan Emergency department Retrospective Suspected acute appendicitis
Kang 1989 [46] 62 Mean 45.8
Range 18 to 78
Male 42
Female
68 China Hospital inpatients Prospective Suspected acute appendicitis
Khan 2005 [29] 100 Mean 20.2
Range 9 to 56
Female 59
Male 41
54 Pakistan Surgical ward Prospective Suspected acute appendicitis
Kim 2006 [9] 211 - - 83 Korea Surgical ward Retrospective Suspected acute appendicitis
Kim 2008 [18] 157 Mean 37.1
Range 15 to 84
- 57 Korea Emergency department Prospective observational study Abdominal pain
Lada 2005 [10] 83 Mean 27.5
Range 15 to 75
Male 43
Female 40
88 Argentina Emergency department Prospective Suspected acute appendicitis
Malik 2000 [56] 100 Mean 22
Range 14 to 18
Male 81
Female 19
92 Pakistan Surgical unit Prospective Suspected acute appendicitis
McKay 2007 [31] 150 Mean 34
Range 18 to 76
Male 78
Female 65
32 USA Emergency department Retrospective Abdominal pain
Memon 2009 [32] 100 Mean age 24
Range 13 to 55
Male 65
Female 35
91 Pakistan Surgical Ward Prospective study Suspected acute appendicitis
Muenzer 2010 [47] 28 Test Cohort Mean 11
Validation cohort
Mean 11
Range 2 to 17
Test cohort Male 10
Female 10
Validation cohort
Male 4
Female 4
54 USA Emergency department Unclear Abdominal pain
Owen 1992 [11] 215   Male 75
Female 70
Children 70
58 Wales Emergency department Prospective observational study GP referral for
Suspected acute appendicitis
Petrosyan 2008 [33] 1,630 Male:
Median 29 yrs
Range 3 to 85 yrs
Female:
Median 34 yrs
Range 2 to 86 yrs
Male 928
Female 702
54 USA Emergency department Retrospective Right lower quadrant pain and suspected acute appendicitis
Rezak 2011 [40] 59 Mean 8.5
Range 3 to 16
Male 43
Female 16
51 USA Community teaching hospital Retrospective Suspected appendicitis
Saidi 2000 [43] 128   Male 49
Female 79
35 Iran Emergency department Prospective Suspected acute appendicitis
Sanabria 2007 [34] 374 Mean 29.5
Range 15 to 71
Male 178
Female 196
55 Columbia Emergency department Prospective Right iliac fossa pain and
suspected acute appendicitis
Schneider 2007 [12] 588 Median 11.9
Range 3 to 21
  33 USA Emergency department Prospective cohort Suspected acute appendicitis
Shreef 2010 [41] 350 Mean 9.3
Range 8 to 14
Male 228
Female 122
38 Egypt, Saudi Arabia Emergency department Prospective Suspected acute appendicitis
Shrivastava 2004 [57] 100   Male 45
Female 30
78 India Emergency department Prospective Suspected acute appendicitis
Singh 2008 [35] 100 Mean 22.6 Median 25 Male 55
Female 45
62 India Surgical Ward Prospective Suspected acute appendicitis
Soomro 2008 [36] 227 Mean 20.47
Range 10 to 62
Male 150
Females 77
55 Pakistan Emergency department Prospective Suspected acute appendicitis
Stephens 1999 [37] 94 Mean 44
Range 3 to 79
Males 46
Female 48
89 USA Surgical unit Retrospective All patients who underwent
appendectomy for
suspected acute appendicitis
Tade 2007 [38] 100 Range 17 to 56 Males 63
Female 37
34 Nigeria Emergency department Prospective Right iliac fossa pain and suspected acute appendicitis
Wani 2007 [30] 96 Mean 25.46
Range 7 to 70
Male 48
Female 48
70 India Surgical unit Prospective Suspected acute appendicitis
Yildirim 2008 [39] 143 Mean 34
Range 18 to 76
Male 78
Females 65
85 Turkey Emergency department Prospective study Abdominal pain
Winn 2004 [58] 142    39 Australia Surgical ward Retrospective Suspected acute appendicitis
Subotic 2008 [59] 57 Mean 27.5
Range 16 to 70
Male 27
Female 30
84 Serbia Emergency department Prospective Suspected acute appendicitis
Andersson 2008 [60] 229 Mean 23 Males 105
Females 124
33 Sweden Emergency department Prospective Suspected acute appendicitis
Prabhudesai 2008 [61] 60 Mean 25.4 Male 27
Female 33
40 UK Emergency department Prospective Suspected acute appendicitis