Table 3 Adjusted geometric mean hormone levels^a of three populations with stratification by body mass index^b

Estradiol, pg/mL

   Low (BMI < 25)

9.5

14.2

15.0

<0.01

   P ^c

<0.01

Reference

0.60

   High (BMI ≥25)

8.2

12.2

14.5

<0.01

   P ^c

<0.01

Reference

0.06

Bioavailable estradiol, %

   Low (BMI <25)

22.4

28.7

17.9

<0.01

   P ^c

<0.01

Reference

<0.01

   High (BMI ≥ 25)

25.6

32.5

23.4

<0.01

   P ^c

<0.01

Reference

<0.01

Estrone, pg/mL

   Low (BMI < 25)

22.5

40.4

32.1

<0.01

   P ^c

<0.01

Reference

<0.01

   High (BMI ≥25)

23.2

38.4

34.2

<0.01

   P ^c

<0.01

Reference

0.19

Sex hormone-binding globulin, nM/L

   Low (BMI < 25)

76.6

62.8

85.8

0.03

   P ^c

0.04

Reference

<0.01

   High (BMI ≥25)

59.6

43.8

59.5

0.03

   P ^c

0.02

Reference

0.02

Androstenedione, ng/mL

   Low (BMI < 25)

0.64

0.63

0.91

0.03

   P ^c

0.90

Reference

0.02

   High (BMI ≥25)

0.76

0.51

1.05

<0.01

   P ^c

0.03

Reference

<0.01

DHEAS, μg/dL

   Low (BMI < 25)

51.9

64.7

48.7

0.21

   P ^c

0.13

Reference

0.11

   High (BMI ≥25)

54.6

52.2

43.4

0.29

   P ^c

0.81

Reference

0.32

Testosterone, ng/mL

   Low (BMI < 25)

0.01

0.07

0.13

<0.01

   P ^c

<0.01

Reference

0.27

   High (BMI ≥25)

0.04

0.15

0.18

<0.01

   P ^c

<0.01

Reference

0.69

Free testosterone, pg/mL

   Low (BMI < 25)

0.18

0.32

0.31

<0.01

   P ^c

<0.01

Reference

0.90

   High (BMI ≥25)

0.26

0.46

0.48

<0.01

   P ^c

<0.01

Reference

0.85