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Table 4 The simple meta-regression analysis to explore heterogeneity for overall response, leucopenia and granulocytopenia according to continuous variables.

From: Risk of infection in patients with lymphoma receiving rituximab: systematic review and meta-analysis

Meta-regression model
Studies characteristics Leucopenia Granulocytopenia Overall response
  Res. Coeff. (95% CI) p Res. Coeff. (95% CI) p Res. Coeff. (95% CI) p
Mean age 0% 0.94
(0.67 to 1.30)
0.237 0% 0.99
(0.97 to 1.00)
0.080 64.7% 0.99
(0.98 to 1.00)
0.271
Number of R cycles 32.9% 0.95
(0.79 to 1.15)
0.561 13.2% 1.03
(0.97 to 1.08)
0.255 66.5% 1.01
(0.97 to 1.05)
0.645
  1. The analysis indicates that mean age may explain heterogeneity found for granulocytopenia and leucopenia. Coeff. = regression coefficient in exponential form; Res. = residual heterogeneity. CI = confidence interval