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Table 5 Clinical-biochemical characteristics of study population according to serum 25(OH) vitamin D quartiles.

From: Strong association between non alcoholic fatty liver disease (NAFLD) and low 25(OH) vitamin D levels in an adult population with normal serum liver enzymes

  I Quartile
(n = 51)
II Quartile
(n = 66)
III Quartile
(n = 62)
IV Quartile
(n = 83)
P-value
Age (years) 55.93 ± 9.34 52.1 ± 10.7 52.2 ± 11.2 52.24 ± 9.45 n.s.
Sex° (M/F) 30/21 32/34 33/29 37/46 n.s.
BMI (kg/m2) 30.99 ± 6.96 29.5 ± 5.8 27.04 ± 4 26.25 ± 4.38 < 0.001
Waist circumference (cm) 105.27 ± 16.82 103.6 ± 14.8 95.01 ± 19.2 91.08 ± 16.72 0.001
FBG (mg/dl) 111.5 ± 26.1 106.3 ± 23.7 107.7 ± 30.2 103.2 ± 31.1 n.s.
Total cholesterol (mg/dl) 206.05 ± 49.46 201.3 ± 41.1 197.5 ± 35.8 192.07 ± 40.95 n.s.
LDL-cholesterol (mg/dl) 122.73 ± 44.62 126.8 ± 37.5 123.6 ± 33.2 109.15 ± 46.07 n.s.
HDL-cholesterol (mg/dl) 51.88 ± 16.36 52.5 ± 12.7 52.5 ± 12.2 52.71 ± 13.82 n.s.
Triglycerides (mg/dl) 178.8 ± 98.7 124.8 ± 84.7 124.6 ± 75 115.6 ± 60.8 0.001
HOMA-IR 10.01 ± 7.58 5.15 ± 4.3 4.3 ± 9.8 5.32 ± 7.86 0.03
AST (IU/l) 21.1 ± 7.4 22.1 ± 11.1 25.6 ± 10.7 21.8 ± 11.01 n.s.
ALT (IU/l) 25.5 ± 14 28.8 ± 16.6 28.6 ± 21.7 26.7 ± 19.2 n.s.
FLI 71.77 ± 26.83 51.9 ± 33.3 45.02 ± 35.9 32.04 ± 29.79 < 0.001
NAFLD ° (%) 68.3 56.1 50 37.3 0.01
MS ° (%) 72.5 43.9 35.5 33.3 < 0.001
T2D ° (%) 36.2 22.7 24.2 25.3 n.s.
  1. Results are shown as mean ± SD. ANOVA test applied. Kruskal-Wallis test applied. HOMA-IR, FBG, triglycerides, AST and ALT were considered as log-values in the analysis. P-values < 0.05 were considered significant.
  2. BMI, body mass index; FBG, fasting blood glucose; LDL, low-density lipoprotein; HDL, high density lipoprotein; HOMA-IR, homeostatis model assessment of insulin resistance; AST, aspartate aminotransferase; ALT, alanine aminotransferase; FLI, fatty liver index; NAFLD, non-alcoholic fatty liver disease; MS, metabolic syndrome; T2D, type 2 diabetes.