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Table 5 Crude, directly standardized, and adjusted annual incidence risk of ME/CFS

From: Prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in three regions of England: a repeated cross-sectional study in primary care

GP Practices ME/CFS cases (n) Population 18 - 64 years old Crude annual incidence risk (‰) Standardized annual incidence riska (‰) Annual incidence risk corrected response ratesb (‰)
    T M F T (95% CI) M (95% CI) F (95% CI) T M F
All practices 13 143,153 0.09 0.04 0.14 0.09 0.05 - 0.15 0.04 0.01 - 0.11 0.13 0.06 - 0.24 0.15 0.06 0.41
London 4 33,047 0.12 0.12 0.13 0.12 0.03 - 0.31 0.10 0.01 - 0.37 0.12 0.01 - 0.43 0.33 0.27 0.31
East Anglia 7 28,026 0.25 0.07 0.44 0.24 0.10 - 0.50 0.07 0 - 0.39 0.38 0.14 - 0.83 0.24 0.07 0.38
East Yorkshire 2 82,080 0.02   0.05 0.02 0 - 0.09    0.05 0.01 - 0.16 0.02   0.05
  1. aReference population: England mid-2008 population (source: Office for National Statistics - http://www.statistics.gov.uk/statbase/product.asp?vlnk%20=%2015106);
  2. bAssumption: The respondents and non-respondents have proportionally the same number of ME/CFS cases; T, Total; M, male; F, female; based on 29 GP clinics.