Skip to main content

Advertisement

Table 7 Reported symptoms in ME/CFS prevalent cases according to compliance with Canadian criteria and non-casesa

From: Prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in three regions of England: a repeated cross-sectional study in primary care

Current symptoms Compliance with Canadian criteria  
  No (n = 97) (%) Yes (n = 125) (%) Non-case (n = 122) (%)
Sleep dysfunction Unrefreshing sleep 93.8d 100.0b 63.1
  Sleep problems 74.2b 97.6 d 56.6
Neurological/Cognitive manifestations Memory/concentration problems 89.7d 97.6b 54.1
  Difficulty thinking 69.1d 93.6 d 42.6
  Unexplained muscle weakness 60.8c 88.0 d 41.0
  Light/noise sensitivity 44.3b 82.4 d 28.7
  Difficulty in understanding things 37.1 77.6 d 32.0
  Confusion or disorientation 28.9 78.4 d 26.2
Pain Pain in two or more joints 89.7d 94.4 d 46.7
  Muscle pain 86.6d 95.2 b 48.4
  Muscle discomfort 82.5d 93.6 b 48.4
  Migratory joint pain 71.1d 87.2 c 40.2
  Headaches 51.5c 76.0 d 32.8
  Migraine 15.5 39.2 d 21.3
Fatigue/tiredness Fatigue after exercise (> 24 hours) 52.6b 100.0 d 37.0
  Intolerance to exercise 50.5b 84.8 d 34.4
  Malaise after exertion (> 24 hours) 41.2b 85.6 d 26.2
Psychological Anxiety 63.0 88.0 d 56.6
  Depression 50.5 75.2 d 41.0
Autonomic Sweatiness/cold hands and feet 42.3 88.8 d 38.5
  Intolerance to be on your feet 38.1b 80.8d 24.6
Immunological Sore throat 37.1 71.2 d 27.0
  Tender glands in the neck/armpits 36.1 73.6 d 27.9
  Mild fever or chills 23.7 77.6 d 29.5
  1. aAll cases met the CDC-1994 criteria; P-values are shown for comparisons of proportions of symptoms between cases that do not conform to the Canadian criteria and non-cases; and between cases that conform to Canadian criteria and non-cases. The following symbols show respective P-values: bP < 0.05; c P < 0.005; d P≤0.001; the results comparing ECD with other diagnostic criteria and non-cases are not presented due to small numbers.