Altered thyroid hormone profile in offspring after exposure to high estradiol environment during the first trimester of pregnancy: a cross-sectional study

Table 2 Physical examination characteristics and medical history of newborns conceived by natural conception (NC), fresh embryo transfer (ET), and frozen ET

		NC	Fresh ET	Frozen ET	P value	P value	P value
		(n = 80)	(n = 55)	(n = 48)	(Fresh ET vs. NC)	(Fresh ET vs. Frozen ET)	(Frozen ET vs. NC)
Singletons/Twins		Singletons	Singletons	Singletons	NS	NS	NS
Gender, n (%)	Boy	41 (51.3%)	27 (49.1%)	23 (47.9%)	NS	NS	NS
Gender, n (%)	Girl	39 (48.7%)	28 (50.9%)	25 (52.1%)	NS	NS	NS
Birth weight (g)		3411 ± 305	3385 ± 488	3404 ± 389	NS	NS	NS
Birth length (cm)		50.03 ± 0.83	49.72 ± 0.81	49.91 ± 0.72	NS	NS	NS
Gestational age (wk)		38.63 ± 0.95	38.37 ± 0.91	38.44 ± 1.04	NS	NS	NS
Preterm delivery (<37 wk), n (%)	No	80 (100%)	55 (100%)	48 (100%)	NS	NS	NS
Preterm delivery (<37 wk), n (%)	Yes	0 (0%)	0 (0%)	0 (0%)	NS	NS	NS
ART method	IVF	/	55 (100%)	48 (100%)	NA	NS	NA
ART method	ICSI	/	0 (0%)	0 (0%)	NA	NS	NA
Maternal age (yr)		30.53 ± 3.17	31.31 ± 3.07	31.73 ± 3.83	NS	NS	NS
Pregnancy complications, n (%)		0	0	0	NS	NS	NS

Data are presented as mean ± SD or n (%), NS, not significant; NA, Not applicable. ART, Assisted reproduction technology; BMI, Body mass index; IVF, In vitro fertilization; ICSI, Intracytoplasmic sperm injection.

ISSN: 1741-7015