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Table 2 Baseline characteristics of selected trials of EGDT in severe sepsis or septic shock

From: Early goal-directed therapy in the management of severe sepsis or septic shock in adults: a meta-analysis of randomized controlled trials

Study

Country

N

Male (%)

Age (y)

Center

Illness severity scores

Overall risk of bias

Andrews 2014 [21]

Zambia

109

53.2

35.2, 34.8

S

APACHE II: 17.8, 17.9

Low

ARISE 2014 [13]

Australia/New Zealand

1,588

59.8

62.7, 63.1

M

APACHE II: 15.4, 15.8

Low

Jing 2010 [8]

China

317

69.3

68.9, 67.7

M

APACHE II: 23.5, 21.8

Low

Jones 2010 [22]

USA

300

54.3

59.8, 61.6

M

SAPS II: 44.8, 44.1

Low

Lin 2006 [23]

Taiwan

224

58.0

67.2, 68.7

S

APACHE III: 66.5, 64.9

Low

ProCESS 2014 [14]

USA

1,341

55.4

60, 62

M

APACHE II: 20.8, 20.7

Low

Rivers 2001 [4]

USA

263

50.6

67.1, 64.4

S

APACHE II: 20.4, 21.4

Low

Wang 2006 [25]

China

33

NA

33, 36

S

APACHE II: 28, 27

Unclear

Wang 2014 [20]

China

57

70.2

52, 56

S

APACHE II: 19.7, 20.9

Unclear

Yu 2013 [24]

China

50

74.0

61, 59

S

APACHE II: 18.2, 17.9

Unclear

  1. Abbreviations:N number of patients, yyear S, single center, M multicenter, APACHE Acute Physiology and Chronic Health Evaluation, SAPS Simplified Acute Physiology Score.