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Table 2 Baseline characteristics of selected trials of EGDT in severe sepsis or septic shock

From: Early goal-directed therapy in the management of severe sepsis or septic shock in adults: a meta-analysis of randomized controlled trials

Study Country N Male (%) Age (y) Center Illness severity scores Overall risk of bias
Andrews 2014 [21] Zambia 109 53.2 35.2, 34.8 S APACHE II: 17.8, 17.9 Low
ARISE 2014 [13] Australia/New Zealand 1,588 59.8 62.7, 63.1 M APACHE II: 15.4, 15.8 Low
Jing 2010 [8] China 317 69.3 68.9, 67.7 M APACHE II: 23.5, 21.8 Low
Jones 2010 [22] USA 300 54.3 59.8, 61.6 M SAPS II: 44.8, 44.1 Low
Lin 2006 [23] Taiwan 224 58.0 67.2, 68.7 S APACHE III: 66.5, 64.9 Low
ProCESS 2014 [14] USA 1,341 55.4 60, 62 M APACHE II: 20.8, 20.7 Low
Rivers 2001 [4] USA 263 50.6 67.1, 64.4 S APACHE II: 20.4, 21.4 Low
Wang 2006 [25] China 33 NA 33, 36 S APACHE II: 28, 27 Unclear
Wang 2014 [20] China 57 70.2 52, 56 S APACHE II: 19.7, 20.9 Unclear
Yu 2013 [24] China 50 74.0 61, 59 S APACHE II: 18.2, 17.9 Unclear
  1. Abbreviations:N number of patients, yyear S, single center, M multicenter, APACHE Acute Physiology and Chronic Health Evaluation, SAPS Simplified Acute Physiology Score.