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Table 1 Baseline characteristics of patients stratified according to outcome (n = 1,521)

From: The predictive value of current haemoglobin levels for incident tuberculosis and/or mortality during long-term antiretroviral therapy in South Africa: a cohort study

  All (n = 1,521) Alive (n = 810) Died (n = 192) LTFU (n = 314) Transfer-out (n = 205) P -value ¥
Age (at baseline), median (IQR) 33 (28-33) 33 (29-38) 35 (29-43) 31 (27-36) 32 (28-38) <0.001#
Gender       
Male 451 (29.7) 235 (29.0) 77 (40.1) 92 (29.3) 47 (22.9) 0.002
Female 1,070 (70.4) 575 (71.0) 115 (59.9) 222 (70.7) 158 (77.1)  
WHO disease stage (at baseline)       
1 or 2 302 (19.9) 184 (22.7) 14 (7.3) 64 (20.4) 40 (19.5) <0.001
3 or 4 1219 (80.1) 626 (77.3) 178 (92.7) 250 (79.6) 165 (80.5)  
CD4 cell count (cells/μL), median, IQR a 101 (49-158) 102 (53-160) 77 (25-138) 108 (53-168) 107 (48-151) <0.001
CD4 category       
≥200 173 (11.6) 98 (12.4) 15 (7.9) 39 (12.8) 21 (10.5) 0.072
100-199 582 (39.1) 311(39.2) 61 (32.1) 126 (41.2) 84 (41.8)  
<100 735 (49.3) 384 (48.4) 114 (60.0) 141 (46.1) 96 (47.8)  
HIV viral load (log copies/mL), median (IQR) b 4.8 (4.4-5.3) 4.8 (4.4-5.2) 5.0 (4.6-5.4) 4.8 (4.3-5.2) 4.8 (4.3-5.2) 0.003
Haemoglobin (g/dL) c       
Median, IQR 11.2 (9.8-12.5) 11.3 (10.0-12.6) 10.5 (9.3-12.3) 11.3 (10.0-12.3) 10.9 (9.7-12.2) 0.028
WHO anaemia severity c       
None 318 (27.9) 185 (30.4) 33 (21.9) 66 (29.0) 34 (22.4) 0.048
Mild 304 (26.7) 163 (26.8) 34 (22.5) 67 (29.4) 40 (26.3)  
Moderate 469 (41.1) 235 (38.6) 74 (49.0) 85 (37.3) 75 (49.3)  
Severe 49 (4.3) 26 (4.3) 10 (6.6) 10 (4.4) 3 (2.0)  
TB disease status       
Past history of TB 710 (46.7) 368 (45.5) 116 (60.4) 133 (42.4) 93 (45.4) 0.001
Prevalent TB 452 (29.7) 211 (26.1) 72 (37.5) 103 (32.8) 66 (32.2) 0.005#
Any incident TB 423 (27.8) 232 (28.6) 59 (30.7) 83 (26.5) 49 (23.9) 0.405
Any TB ever (including past history, prevalent and incident TB) 1,147(75.4) 599 (74.0) 165 (85.9) 229 (72.9) 154 (75.1) 0.004
  1. Abbreviations:IQR interquartile range, TB tuberculosis, WHO World Health Organization.
  2. a31 missing values, b101 missing values, c 381 missing values.
  3. All values are numbers (%) unless otherwise stated.
  4. ¥P-value tests for a difference across all groups; #P-value < 0.05 for a difference between those who were LTFU during ART and those who remained alive and in programme. There was no evidence to suggest a difference (P < 0.05) between any baseline characteristics of those who transferred out of the ART programme and those who remained alive and in programme.