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Table 2 Patient characteristics associated with dispensing of ≥10 drugs in 2010*

From: The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995–2010

Variable (no. of patients) Proportion (95% CI) dispensed ≥10 drugs Univariate multilevel odds ratio (95% CI) Adjusted multilevel odds ratio (95% CI)
Age groups (years)    
20–29 (n = 51,197) 0.3 (0.2–0.3) Reference Reference
30–39 (n = 47,857) 0.7 (0.6–0.8) 2.81 (2.31–3.41) 2.91 (2.38–3.56)
40–49 (n = 60,077) 1.7 (1.5–2.0) 6.78 (5.69–8.09) 7.16 (5.98–8.58)
50–59 (n = 52,751) 4.1 (3.6–4.6) 16.9 (14.2–20.0) 18.0 (15.1–21.5)
60–69 (n = 47,080) 8.7 (7.9–9.4) 38.1 (32.2–45.2) 41.1 (34.6–48.8)
70–79 (n = 32,986) 17.1 (16.1–18.2) 83.4 (70.5–98.7) 87.5 (73.7–104.0)
80+ (n = 19,933) 24.0 (22.9–25.1) 130.0 (10.9.8–153.9) 118.3 (99.5–140.7)
Sex    
Male (n = 151,202) 4.6 (4.3–4.8) Reference Reference
Female (n = 160,679) 7.0 (6.7–7.4) 1.59 (1.54–1.64) 1.34 (1.30–1.39)
Deprivation quintile    
1 (affluent) (n = 56,416) 4.9 (4.5–5.4) Reference Reference
2 (n = 94,090) 5.3 (5.0–5.7) 1.13 (1.07–1.19) 1.21 (1.14–1.28)
3 (n = 53,990) 5.3 (5.0–5.6) 1.04 (0.99–1.10) 1.32 (1.24–1.39)
4 (n = 49,387) 6.4 (6.0–6.7) 1.33 (1.26–1.40) 1.70 (1.61–1.79)
5 (deprived) (n = 50,877) 7.6 (7.1–8.1) 1.58 (1.49–1.67) 2.36 (2.22–2.51)
SEURC category #    
Primary city (n = 121,804) 6.5 (6.1–6.9) Reference Reference
Urban area (n = 80,401) 6.0 (5.5–6.5) 0.91 (0.84–1.00) 0.96 (0.88–1.05)
Accessible area (n = 78,490) 5.0 (4.6–5.4) 0.74 (0.69–0.80) 0.84 (0.78–0.92)
Remote area (n = 24,268) 5.7 (5.0–6.3) 0.85 (0.75–0.96) 0.83 (0.73–0.94)
Living    
In own home (n = 308,660) 5.5 (5.2–5.8) Reference Reference
In care home (n = 3,221) 36.5 (33.8–39.1) 9.91 (9.21–10.67) 2.88 (2.65–3.13)
  1. *Practice level variables not significant in either univariate or adjusted models (list size, accreditation for postgraduate training, dispensing medicines [marginally significant association in univariate analysis], type of NHS contract).
  2. #Scottish Executive Urban–rural Classification.