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Table 1 Baseline characteristics of included participants from the Rotterdam Study evaluating the association between thyroid function and AMD*

From: Thyroid function and age-related macular degeneration: a prospective population-based cohort study - the Rotterdam Study

Variable No incident AMD Incident AMD  
  N = 4,768 N = 805 P -value**
Age, years 67.6 (7.6) 67.9 (7.1) 0.29
Sex, % female 57.6 57.8 0.94
History of diabetes, % 10.8 8.4 0.04
BMI, kg/m2 26.9 (3.9) 26.6 (3.7) 0.07
Cholesterol, mmol/L 6.1 (1.2) 6.1 (1.1) 0.23
Smoking, % current 20.7 21.0 0.85
Hypertension, % 63.0 58.7 0.17
TSH, mIU/L median (IQR) 1.78 (1.15-2.69) 1.73 (1.17-2.67) 0.78
FT4, pmol/L 15.8 (2.6) 16.0 (3.2) 0.13
TPOAb, kU/L 30.5 (95.1) 30.8 (96.2) 0.93
  1. *Values are means and SD unless otherwise specified.
  2. **For comparison a t-test was conducted, for TSH the log-transformed values were used.
  3. Abbreviations: AMD age-related macular degeneration BMI body mass index, TSH thyroid-stimulating hormone, FT4 = free thyroxine, SD standard deviation, IQR interquartile range, TPOAb thyroid peroxidase antibodies.