|
Incident AMD versus no AMD
|
AMD N
|
Total N
|
HR (95% CI), model 1
|
HR (95% CI), model 2
|
HR (95% CI), model 3
|
|---|
|
Excluded thyroid medication
| | | | | |
|
Free T4
|
752
|
5,225
|
1.03 (1.01-1.06)
|
1.03 (1.01-1.06)
|
1.03 (1.01-1.06)
|
|
TSH, mIU/L
|
778
|
5,417
|
0.99 (0.91-1.08)
|
1.00 (0.92-1.09)
|
1.00 (0.91-1.09)
|
|
Excluding baseline thyroid diseaseb
| | | | | |
|
Free T4
|
751
|
5,237
|
1.04 (1.01-1.08)
|
1.04 (1.01-1.07)
|
1.04 (1.01-1.08)
|
|
TSH, mIU/L
|
764
|
5,300
|
0.98 (0.89-1.07)
|
0.98 (0.89-1.07)
|
0.97 (0.89-1.07)
|
- a155 participants had thyroid medication (thyroid hormone use) at baseline.
- b272 participants had self-reported thyroid disease at baseline.
- Model 1: Adjusted for sex and age. Model 2: Model 1 + smoking, hypertension, cholesterol, diabetes, BMI. Model 3: Model 2 + thyroid peroxidase antibodies positivity.
- Abbreviations: BMI body mass index, CI confidence interval, FT4 free thyroxine, HR hazard ratio, TSH thyroid-stimulating hormone.
