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Table 5 Mutually adjusted hazard ratios (HR) and 95% confidence intervals (95% CIs) for CRC-related and overall mortality among CRC survivors, associated with the components of the WCRF/AICR score

From: Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study

  CRC-related mortality Overall mortality
  HR a 95% CI P for trend b HR a 95% CI P for trend b
Body fatness       
0 1.00 (ref) 0.010 1.00 (ref) 0.006
0.5 0.88 (0.73–1.06)   0.84 (0.71–0.99)  
1 0.78 (0.64–0.95)   0.78 (0.66–0.94)  
Physical activity       
0 1.00 (ref) 0.069 1.00 (ref) 0.162
0.5 0.86 (0.70–1.06)   0.84 (0.69–1.01)  
1 0.87 (0.74–1.02)   0.91 (0.79–1.05)  
Foods that promote weight gain       
0 1.00 (ref) 0.683 1.00 (ref) 0.544
0.25 0.87 (0.60–1.26)   0.80 (0.58–1.10)  
0.5 0.93 (0.64–1.33)   0.88 (0.64–1.21)  
0.75 0.87 (0.59–1.28)   0.84 (0.60–1.17)  
1 1.03 (0.64–1.69)   0.98 (0.64–1.51)  
Plant foods       
0 1.00 (ref) 0.069 1.00 (ref) 0.119
0.25 0.73 (0.56–0.97)   0.76 (0.60–0.97)  
0.5 0.66 (0.51–0.86)   0.72 (0.60–0.91)  
0.75 0.79 (0.60–1.02)   0.86 (0.68–1.09)  
1 0.65 (0.49–0.87)   0.68 (0.53–0.89)  
Animal foods       
0 1.00 (ref) 0.156 1.00 (ref) 0.123
0.5 1.14 (0.97–1.35)   1.09 (0.94–1.26)  
1 1.12 (0.83–1.51)   1.19 (0.92–1.54)  
Alcohol intake       
0 1.00 (ref) 0.658 1.00 (ref) 0.726
0.5 1.00 (0.78–1.28)   1.00 (0.81–1.25)  
1 0.95 (0.79–1.14)   0.96 (0.82–1.12)  
Breastfeeding c       
0 1.00 (ref) 0.089 1.00 (ref) 0.407
0.5 0.68 (0.53–0.88)   0.76 (0.60–0.95)  
1 0.80 (0.63–1.02)   0.91 (0.73–1.13)  
  1. aCox regression model, with age at CRC diagnosis as entry time and age at death or censoring as exit time, stratified by country and adjusted for year of CRC diagnosis, tumor stage, tumor grade, tumor site, sex, educational level, and smoking status. All components were mutually adjusted for each other. bP for trend was calculated by modelling components of the WCRF/AICR score as continuous variables. cIn women only.