Table 3 Statistically significant results of network meta-analysis for all time periods of drug administration
| Â | All ages | Children only | ||||
|---|---|---|---|---|---|---|
Treatment comparison | Number of studies | MA estimate: OR (95 % CI) | NMA estimate: OR (95 % CI) | Number of studies | MA estimate: OR (95 % CI) | NMA estimate: OR (95 % CI) |
Arrhythmia | 31 RCTs and 6,623 patients | 9 RCTs and 1,572 patients | ||||
Granisetron + DEX vs placebo | 2 | 2.63 (0.75– 9.29) | 2.96 (1.11–7.94) | 1 | 4.89 (1.15–20.79) | 5.15 (1.33–19.91) |
Granisetron + DEX vs ondansetron | NA | NA | 3.23 (1.17–8.95) | NA | NA | 4.71 (1.08–20.46) |
Granisetron + DEX vs dolasetron | NA | NA | 4.37 (1.51–12.62) | NA | NA | NA |
Granisetron + DEX vs tropisetron | NA | NA | 3.27 (1.02–10.43) | NA | NA | NA |
Granisetron + DEX vs ondansetron + DEX | 2 | 8.10 (1.92–34.13) | 5.75 (1.71–19.34) | 1 | 7.67 (1.47–40.00) | 7.12 (1.66–30.63) |