Skip to main content

Table 8 Comparing rates of tuberculosis in 198,227 patients with type 2 diabetes (T2DM) and HbA1c measurements with a matched unexposed cohort

From: Risk of tuberculosis in patients with diabetes: population based cohort study using the UK Clinical Practice Research Datalink

   

Age adjusted

 

Fully adjusted modela

 

Exposure group

Number of patients

TB cases/PYb

Ratec (95 % CI)

Rate ratio

Rate ratio

P-value*

(% of T2DM)

(95 % CI)

(95 % CI)

Patients without diabetes

1,088,376

689/50.97

13.51 (12.54–14.56)

1.00

1.00

 

Patients with T2DM

      

HbA1c mmol/mol (%):

      

≤48 (6.5)

61,336 (30.9)

50/2.86

17.48 (13.25–23.06)

1.29 (0.97–1.72)

1.34 (0.88–2.05)

0.140

49- ≤ 58 (6.5–7.5)

70,470 (35.6)

54/3.98

13.57 (10.39–17.72)

1.00 (0.76–1.32)

1.14 (0.76–1.70)

 

>58 (>7.5)

66,421 (33.5)

71/3.99

17.81 (14.12–22.48)

1.32 (1.03–1.68)

1.50 (1.04–2.17)

 
  1. *P-value from likelihood ratio test
  2. aModel adjusted for: age, BMI, smoking status, alcohol status, ethnicity and IMD
  3. bPY: 100,000 person years at risk
  4. cRate: per 100,000 person years
  5. BMI body mass index, CI confidence interval, IMD index of multiple deprivation, TB tuberculosis
Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us