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Table 2 Diagnostic performance of troponin I measured upon admission in the validation cohort

From: Identification of acute myocardial infarction in patients with atrial fibrillation and chest pain with a contemporary sensitive troponin I assay

Troponin I threshold optimized for Cut-off Sensitivity Specificity PPV NPV
[ng/mL] (95% CI) (95% CI) (95% CI) (95% CI)
Sensitivity 0.019 0.90 (0.80-0.96) 0.88 (0.84-0.92) 0.66 (0.55-0.76) 0.97 (0.94-0.99)
Specificity 0.09 0.69 (0.56-0.80) 0.98 (0.95-0.99) 0.88 (0.75-0.95) 0.93 (0.89-0.96)
Unweighted 0.04 0.82 (0.70-0.91) 0.92 (0.88-0.95) 0.73 (0.61-0.83) 0.95 (0.92-0.98)
99th percentile threshold 0.032 0.85 (0.74-0.93) 0.91 (0.87-0.94) 0.71 (0.59-0.81) 0.96 (0.93-0.98)
  1. Cut-offs applied are derived from the derivation cohort optimized with respect to high sensitivity and high specificity or are unweighted compared with the 99th percentile cut-off of the assay used. 95 % CI denotes 95 % confidence interval