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Table 2 Patient characteristics

From: Rapid microbiological screening for tuberculosis in HIV-positive patients on the first day of acute hospital admission by systematic testing of urine samples using Xpert MTB/RIF: a prospective cohort in South Africa

Characteristic All patients Patients with a TB diagnosis Patients without a TB diagnosis P value
(n = 427) (n = 139) (n = 288)
 Age (years), median (IQR) 36.1 (28.9–42.4) 33.8 (27.2–39.7) 37.1 (30.0–44.0) 0.008
 Female 259 (60.7) 90 (64.8) 169 (58.7) 0.229
 New HIV diagnosis on admission 82 (19.2) 34 (24.5) 48 (16.7) 0.055
 History of previous TBa 196 (46.1) 50 (36.2) 146 (50.9) 0.005
ART status
 ART-naive 177 (41.5) 71 (51.1) 106 (36.8) 0.019
 ART interrupted 71 (16.6) 19 (13.7) 52 (18.1)  
 Current ART use 179 (41.9) 49 (35.3) 130 (45.1)  
 If currently on ART, treatment duration (years), median (IQR) 1.6 (0.6–3.6) 1.3 (0.2–2.9) 1.7 (0.6–3.7) 0.157
CD4 cell count (cells/uL) (n = 424)
 Median (IQR) cells/μL 149 (55–312) 80 (33–182) 191 (73–392) <0.001
 <50 94 (22.2) 53 (38.4) 41 (14.3)  
 50–99 66 (15.6) 21 (15.2) 45 (15.7)  
 100–149 53 (12.5) 19 (13.8) 34 (11.9)  
 150–199 42 (9.9) 16 (11.6) 26 (9.1)  
 ≥200 169 (39.9) 29 (21.0) 140 (49.0)  
Haemoglobin levels (n = 421)
 Median (IQR) 9.6 (7.7–11.6) 8.4 (6.8–10.2) 10.2 (8.2–12.2) <0.001
 No/mild anaemia 144 (34.2) 28 (20.1) 116 (41.1)  
 Moderate/severe anaemia 277 (65.8) 111 (79.9) 166 (58.9)  
Symptoms
 Cough ≥2 weeksa 34 (8.0) 18 (13.0) 16 (5.6) 0.008
 Sputum productiona 161 (38.3) 51 (37.5) 110 (38.7) 0.808
 Current cougha 201 (47.4) 84 (60.9) 117 (40.9) <0.001
 Current fevera 63 (14.9) 24 (17.5) 39 (13.6) 0.294
 Current night sweatsa 174 (41.0) 73 (52.9) 101 (35.3) 0.001
 Current reported weight lossa 189 (44.5) 76 (55.1) 113 (39.4) 0.002
 Positive WHO symptom screena 389 (91.5) 134 (97.1) 255 (88.9) 0.005
  1. Data presented are numbers (%) unless otherwise stated. aBetween two and seven values missing. IQR, interquartile range