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Table 2 Patient characteristics

From: Rapid microbiological screening for tuberculosis in HIV-positive patients on the first day of acute hospital admission by systematic testing of urine samples using Xpert MTB/RIF: a prospective cohort in South Africa

Characteristic

All patients

Patients with a TB diagnosis

Patients without a TB diagnosis

P value

(n = 427)

(n = 139)

(n = 288)

 Age (years), median (IQR)

36.1 (28.9–42.4)

33.8 (27.2–39.7)

37.1 (30.0–44.0)

0.008

 Female

259 (60.7)

90 (64.8)

169 (58.7)

0.229

 New HIV diagnosis on admission

82 (19.2)

34 (24.5)

48 (16.7)

0.055

 History of previous TBa

196 (46.1)

50 (36.2)

146 (50.9)

0.005

ART status

 ART-naive

177 (41.5)

71 (51.1)

106 (36.8)

0.019

 ART interrupted

71 (16.6)

19 (13.7)

52 (18.1)

 

 Current ART use

179 (41.9)

49 (35.3)

130 (45.1)

 

 If currently on ART, treatment duration (years), median (IQR)

1.6 (0.6–3.6)

1.3 (0.2–2.9)

1.7 (0.6–3.7)

0.157

CD4 cell count (cells/uL) (n = 424)

 Median (IQR) cells/μL

149 (55–312)

80 (33–182)

191 (73–392)

<0.001

 <50

94 (22.2)

53 (38.4)

41 (14.3)

 

 50–99

66 (15.6)

21 (15.2)

45 (15.7)

 

 100–149

53 (12.5)

19 (13.8)

34 (11.9)

 

 150–199

42 (9.9)

16 (11.6)

26 (9.1)

 

 ≥200

169 (39.9)

29 (21.0)

140 (49.0)

 

Haemoglobin levels (n = 421)

 Median (IQR)

9.6 (7.7–11.6)

8.4 (6.8–10.2)

10.2 (8.2–12.2)

<0.001

 No/mild anaemia

144 (34.2)

28 (20.1)

116 (41.1)

 

 Moderate/severe anaemia

277 (65.8)

111 (79.9)

166 (58.9)

 

Symptoms

 Cough ≥2 weeksa

34 (8.0)

18 (13.0)

16 (5.6)

0.008

 Sputum productiona

161 (38.3)

51 (37.5)

110 (38.7)

0.808

 Current cougha

201 (47.4)

84 (60.9)

117 (40.9)

<0.001

 Current fevera

63 (14.9)

24 (17.5)

39 (13.6)

0.294

 Current night sweatsa

174 (41.0)

73 (52.9)

101 (35.3)

0.001

 Current reported weight lossa

189 (44.5)

76 (55.1)

113 (39.4)

0.002

 Positive WHO symptom screena

389 (91.5)

134 (97.1)

255 (88.9)

0.005

  1. Data presented are numbers (%) unless otherwise stated. aBetween two and seven values missing. IQR, interquartile range