Coffee consumption, cups/day | ||||||
---|---|---|---|---|---|---|
<2 (1)a | 2 to <3 (2) | 3 to <4 (3) | 4 to <5 (4) | ≥5 (6) | P trend | |
Men (n = 41,881) | ||||||
Number of cases | 742 | 1,155 | 813 | 715 | 886 | |
Person-years | 69,946 | 106,314 | 83,602 | 78,990 | 110,892 | |
Age-adjusted RR (95 % CI) | 1.00 | 0.97 (0.88–1.06) | 0.93 (0.84–1.03) | 0.90 (0.81–1.00) | 1.02 (0.92–1.12) | 0.74 |
Multivariable RR (95 % CI)b | 1.00 | 0.99 (0.90–1.09) | 0.99 (0.89–1.09) | 0.97 (0.87–1.07) | 1.08 (0.98–1.20) | 0.10 |
Women (n = 34,594) | ||||||
Number of cases | 505 | 804 | 617 | 473 | 331 | |
Person-years | 62,699 | 104,866 | 84,552 | 66,627 | 63,256 | |
Age-adjusted RR (95 % CI) | 1.00 | 0.94 (0.84–1.05) | 0.95 (0.85–1.07) | 0.96 (0.85–1.09) | 0.89 (0.77–1.02) | 0.17 |
Multivariable RR (95 % CI)b | 1.00 | 0.95 (0.85–1.07) | 0.98 (0.87–1.10) | 0.98 (0.86–1.12) | 0.88 (0.76–1.02) | 0.17 |
Men and women combined | ||||||
Multivariable RR (95 % CI)b | 1.00 | 0.98 (0.91–1.05) | 0.99 (0.91–1.07) | 0.97 (0.90–1.05) | 1.01 (0.93–1.10) | 0.64 |