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Table 2 Validation cohort 1: clinical characteristics of patients for tissue microarray experiment

From: Chemotherapy reduces PARP1 in cancers of the ovary: implications for future clinical trials involving PARP inhibitors

Patients

Number (%)

Number

170

Age (years), mean (range)

52 (39–93)

Histology

Serous

150 (88.2)

Non serous

20 (11.8)

Stage

I

7 (4.1)

II

11 (6.4)

III

129 (72.9)

IV

21 (12.3)

Grade

1

6 (3.5)

2

22 (12.9)

3

136 (80)

Chemotherapy

Neo-adjuvant

85 (50)

Adjuvant

85 (50)

Residual disease

≤1 cm

87 (51.2)

≥1 cm

57 (33.5)

Not determined

26 (15.3)

Response

Responsive

123 (72.3)

Resistant

47 (27.7)

Recurrence

Number

128 (75.3)

Mean time (range)

20 months (2–76)

Deceased

Number

105 (61.8)

Mean time (range)

47 months (2–156)

Follow up

Mean time (range)

43 months (2–73)