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Fig. 2 | BMC Medicine

Fig. 2

From: RNY-derived small RNAs as a signature of coronary artery disease

Fig. 2

s-RNY expression is induced in atherosclerotic areas and in smooth muscle foam cells. a RT-qPCR analysis of s-RNY1-5p in ApoE −/− aortic arches and femoral arteries. The data were normalized by U2 snRNA and are presented as mean and standard deviation (n per group = 5). b RT-qPCR analysis of the indicated s-RNYs in CRL 2797 cells (smooth muscle cells; left panel, n per group = 6), CRL 2181 cells (endothelial cells; central panel, n per group = 7), primary myocardial cells (right panel, n per group = 3) incubated for 28 h with 0.25 μM thapsigargin in combination with the indicated concentration of acetylated LDL and control. The data were normalized by U2 snRNA and are presented as mean and standard deviation. Student’s t-test: *P <0.05, **P <0.01

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