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Fig. 6 | BMC Medicine

Fig. 6

From: RNY-derived small RNAs as a signature of coronary artery disease

Fig. 6

Circulating s-RNY4-5p expression is induced in patients with coronary artery disease (CAD). a Box plot showing the expression in natural logarithmic scale of circulating s-RNY4-5p in the serum of CAD patients (n = 45) versus control individuals (CTL, n = 45). Data derived from RT-qPCR were normalized using cel-miR-39, and presented as mean and standard deviation. b Receiver operating characteristic (ROC) curve for predicting CAD with s-RNY4-5p. The ROC curve was constructed using s-RNY4-5p based on the RT-qPCR data (n = 90). The area under the ROC curve is given and 95 % confidence interval was indicated in square brackets. Student’s t-test: ***P <0.001

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