Fig. 6

Mean rounds of annual MDAs in years for achieving LF elimination in each study site. The left and right heat maps are, respectively, for the anopheline and culicine settings. Two intervention scenarios (namely, MDA alone and MDA + VC, with VC coverage at 80 %) were modeled using three mf breakpoint threshold values at 50 %, 75 % and 95 % elimination probabilities (see Table 3). The results are shown for three MDA coverages at 60 %, 80 % and 100 % for the MDA alone in the first three columns and for the MDA + VC strategy in the remaining three columns of both the left- and right-panel plots. The drug regimens and their respective efficacies (i.e. adult worm and mf killing rates and efficacious period) used in modeling these intervention scenarios are given in Table 1. The mean number of years of interventions were derived using model runs for each of the 18 study sites based on their site-specific best-fit parameter vectors. EP, elimination probability; MDA, mass drug administration; VC, vector control