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Table 3 Diagnostic performance of CRP in diagnosing serious infection at different thresholds by randomisation arm

From: Should all acutely ill children in primary care be tested with point-of-care CRP: a cluster randomised trial

  CRP in all children CRP only in children at clinical risk
Missed cases n/N % 95 % CI n/N % 95 % CI
 ≥ 5 mg/L 0/7 0 0.0–40.9 0/4 0 0.0–60.2
 ≥ 20 mg/L 3/7 42.9 9.9–81.6 3/4 75 19.4–99.4
 ≥ 80 mg/L 6/7 85.7 42.1–99.6 4/4 100 39.7–100
 ≥ 200 mg/L 6/7 85.7 42.1–99.6 4/4 100 39.7–100
False alarms n/N % 95 % CI n/N % 95 % CI
 ≥ 5 mg/L 918/1723 53.3 49.9–56.8 161/281 57.3 51.3–63.2
 ≥ 20 mg/L 448/1723 26.0 23.9–28.1 85/281 30.2 24.9–36.0
 ≥ 80 mg/L 65/1723 3.8 2.9–4.8 14/281 5.0 2.8–8.2
 ≥ 200 mg/L 2/1723 0.1 0.0–0.4 2/281 0.7 0.0–2.5
  1. CRP point-of-care CRP testing, 95 % CI 95 % confidence intervals