Table 3 Diagnostic performance of CRP in diagnosing serious infection at different thresholds by randomisation arm
CRP in all children | CRP only in children at clinical risk | |||||
|---|---|---|---|---|---|---|
Missed cases | n/N | % | 95 % CI | n/N | % | 95 % CI |
≥ 5 mg/L | 0/7 | 0 | 0.0–40.9 | 0/4 | 0 | 0.0–60.2 |
≥ 20 mg/L | 3/7 | 42.9 | 9.9–81.6 | 3/4 | 75 | 19.4–99.4 |
≥ 80 mg/L | 6/7 | 85.7 | 42.1–99.6 | 4/4 | 100 | 39.7–100 |
≥ 200 mg/L | 6/7 | 85.7 | 42.1–99.6 | 4/4 | 100 | 39.7–100 |
False alarms | n/N | % | 95 % CI | n/N | % | 95 % CI |
≥ 5 mg/L | 918/1723 | 53.3 | 49.9–56.8 | 161/281 | 57.3 | 51.3–63.2 |
≥ 20 mg/L | 448/1723 | 26.0 | 23.9–28.1 | 85/281 | 30.2 | 24.9–36.0 |
≥ 80 mg/L | 65/1723 | 3.8 | 2.9–4.8 | 14/281 | 5.0 | 2.8–8.2 |
≥ 200 mg/L | 2/1723 | 0.1 | 0.0–0.4 | 2/281 | 0.7 | 0.0–2.5 |