Variables
|
Overall
|
Metabolic syndrome
|
Non-metabolic syndrome
|
P value
|
---|
Sample size
|
1212
|
781
|
431
| |
Age, years
|
53.3 ± 7.3
|
54.3 ± 7.2
|
51.6 ± 7.2
|
< 0.001
|
Gender (male), n (%)
|
347 (28.6)
|
251 (32.1)
|
96 (22.3)
|
< 0.001
|
BMI, kg/m2
|
27.1 ± 2.7
|
27.4 ± 2.8
|
26.6 ± 2.6
|
< 0.001
|
Waist circumference, cm
|
93.8 ± 7.2
|
94.7 ± 7.4
|
92.2 ± 6.6
|
< 0.001
|
Current smokers, n (%)
|
158 (13.0)
|
104 (13.3)
|
54 (12.5)
|
0.445
|
Systolic BP, mmHg
|
133.3 ± 17.5
|
139.2 ± 16.4
|
122.6 ± 14.2
|
< 0.001
|
Diastolic BP, mmHg
|
79.3 ± 10.6
|
82.3 ± 10.3
|
73.7 ± 8.7
|
< 0.001
|
Triglycerides, mmol/L
|
1.6 (1.1–2.3)
|
1.9 (1.4–2.7)
|
1.5 (1.1–2.0)
|
< 0.001
|
Total cholesterol, mmol/L
|
5.9 ± 1.1
|
6.0 ± 1.1
|
5.7 ± 1.0
|
< 0.001
|
LDL- cholesterol, mmol/L
|
3.7 ± 1.0
|
3.7 ± 1.0
|
3.6 ± 0.9
|
0.533
|
HDL-cholesterol, mmol/L
|
1.4 ± 0.3
|
1.3 ± 0.3
|
1.5 ± 0.3
|
< 0.001
|
Fasting glucose, mmol/L
|
6.1 ± 1.7
|
6.5 ± 1.9
|
5.5 ± 0.9
|
< 0.001
|
2-h glucose, mmol/L
|
9.0 ± 4.0
|
9.9 ± 4.4
|
7.2 ± 2.3
|
< 0.001
|
HOMA-IR
|
2.92 (2.10–4.25)
|
2.81 (2.04–4.04)
|
2.83 (1.84–3.99)
|
< 0.001
|
Serum Nrg4, ng/mL
|
3.35 (2.47–4.74)
|
3.24 (2.40–4.52)
|
3.55 (2.60–5.29)
|
0.002
|
Body fat mass, kg
|
24.0 ± 5.3
|
24.3 ± 5.4
|
23.5 ± 5.1
|
0.013
|
- Data are presented as the mean ± SD or median (interquartile range)
- BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance, Nrg4 Neuregulin 4