Table 3 Summary of enrichment analysis for the top 1573 differentially expressed genes between groups II and III (p < 0.05)
MetaCoreTM process network | Upregulated in group II (n = 957) | Downregulated in group II (n = 616) |
|---|---|---|
Term | p value (nupregulated/ntotal) | p value (ndownregulated/ntotal) |
Blood vessel morphogenesis | 0.058 (10/228) | 2.14E-07 (20/228) |
Muscle contraction | 1.22E-03 (12/173) | 0.411 (7/173) |
Male sex differentiation | 0.087 (10/246) | 1.50E-03 (14/246) |
Transmission of nerve impulse | 2.36E-03 (13/212) | 0.360 (6/212) |
Neurogenesis | 2.95E-03 (12/192) | 0.452 (5/192) |
Chemotaxis | 0.669 (3/137) | 4.13E-03 (9/137) |
Anti-apoptosis via PI3K/Akt | 0.982 (2/233) | 7.16E-03 (12/233) |
Leukocyte chemotaxis | 0.891 (3/205) | 7.36E-03 (11/205) |
Neurohormone signaling | 0.273 (7/211) | 9.06E-03 (11/211) |
Inflammation - IL-2 signaling | 0.482 (3/104) | 9.73E-03 (7/104) |