Cost parameters

Multimodal screening (dropouts)

£54

Beta

£33 to £74

Multimodal screening (complete screening)

£61

Hybrid^{a}

£37 to £83

Ultrasound screening (dropouts)

£56

Gamma

£29 to £92

Ultrasound screening (complete screening)

£61

Hybrid^{a}

£31 to £100

Screening invitation (either strategy)

£2.09

Gamma

£1.70 to £2.52

Diagnosis: Borderline

£110

Gamma

£91 to £135

Diagnosis: Stage 1 ovarian cancer

£116

Gamma

£90 to £133

Diagnosis: Stage 2 ovarian cancer

£126

Gamma

£94 to £140

Diagnosis: Stage 3 ovarian cancer

£126

Gamma

£102 to £152

Diagnosis: Stage 4 ovarian cancer

£112

Gamma

£102 to £152

Treatment: Borderline

£3000

Gamma

£1161 to £5696

Treatment: Stage 1 ovarian cancer

£6961

Gamma

£4856 to £9438

Treatment: Stage 2 ovarian cancer

£7325

Gamma

£5211 to £9795

Treatment: Stage 3 ovarian cancer

£9016

Gamma

£6866 to £11,454

Treatment: Stage 4 ovarian cancer

£5892

Gamma

£3823 to £8402

End of life cost: ovarian cancer

£7080

Gamma

£5761 to £8533

Utility parameters

Utility cancer free

0. 900

Beta

0.325 to 1

Disutility Stage 1 ovarian cancer or false positive result

0.200

Beta

0.044 to 0.437

Disutility Stage 2 ovarian cancer

0.325

Beta

0.214 to 0.534

Disutility Stage 3 ovarian cancer

0.413

Beta

0.329 to 0.600

Disutility Stage 4 ovarian cancer

0. 455

Beta

0.413 to 0.601

Number of false positives per cancer identified

Multimodal screening

2.302

Beta

2.188 to 2.412

Ultrasound screening

9.963

Beta

9.813 to 10.104
