Subgroup | Analysis of medians | Analysis of pooled average | |||
---|---|---|---|---|---|
Range, mm | Number of studiesa (patientsb) | MCID Median, mm (IQR) | Number of studies (patientsb) | MCID pooled average, mm (95% CI), I2 c | |
All studies | 8–40 | 29 (6517) | 17 (14–23) | 23 (6024) | 17 (15–19), 93% |
Clinical conditions | |||||
 Post-operation paind | 9–29 | 7 (731) | 18 (10–25) | 3 (361) | 11 (8–14), 42% |
 Trauma | 16–20 | 2 (125) | 18 (16–20) | 2 (125) | 18 (15–22), 11% |
 Abdominal pain | 18–25 | 2 (407) | 21 (18–25) | 2 (407) | 21 (15–28), 91% |
 Mixed patients at ED | 8–24 | 7 (2418) | 15 (11–21) | 6 (2345) | 16 (12–20), 90% |
 Othere | 10–40 | 5 (1980) | 27 (23–34) | 4 (1930) | 22 (15–29), 92% |
 Unspecified | 13–21 | 6 (856) | 16 (14–16) | 6 (856) | 16 (14–18), 72% |
Definition of MCID | |||||
 One category improvement | 8–34 | 24 (4504) | 16 (13–21) | 22 (4281) | 16 (14–18), 91% |
 Several categories improvement | 23–29 | 3 (220) | 25 (23–29) | NA | NA |
 Meaningful change | 27–40 | 2 (1793) | 34 (27–40) | 1 (1743) | 27 (25–29), NA |
Directionality of transition scale | |||||
 One-sided | 9–40 | 5 (538) | 18 (13–21) | 3 (383) | 15 (8–21), 93% |
 Two-sided | 8–25 | 19 (3962) | 16 (13–20) | 18 (3844) | 16 (14–19), 91% |
Pain scale | |||||
 Visual Analogue Scale | 8–40 | 17 (3232) | 17 (13–25) | 15 (3109) | 16 (13–19), 91% |
 Numeric Rating Scale | 10–23 | 7 (1268) | 15 (14–21) | 6 (1118) | 16 (14–19), 91% |
Measurements per patient | |||||
 Single | 18–40 | 4 (461) | 25 (23–29) | 4 (2058) | 22 (19–25), 0% |
 Multiple | |||||
  With adjustment | 10–18 | 9 (1104) | 15 (13–16) | 8 (1031) | 15 (13–16), 34% |
  Without Adjustment/unclear | 8–25 | 11 (2935) | 16 (10–21) | 11 (2935) | 16 (13–20), 95% |
Risk of attrition bias | |||||
 Low | 8–40 | 8 (1249) | 19 (15–25) | 8 (1249) | 16 (14–18), 81% |
 High or unclear | 9–25 | 16 (3251) | 16 (12–19) | 13 (2978) | 16 (13–19), 93% |
Risk of non-representative sampling | |||||
 Low | 8–25 | 6 (1187) | 16 (10–21) | 6 (1187) | 16 (11–21), 96% |
 High or unclear | 9–40 | 18 (3313) | 18 (14–24) | 15 (3040) | 16 (14–18), 87% |