Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models

Table 3 Comparison of observed and predicted probability of survival using PREP-S model at 48 hours and by 1 week after diagnosis of early onset pre-eclampsia in external datasets

Risk stratification (No. of women)	Time	External validation in PIERS cohort
Risk stratification (No. of women)	Time	Observed survival probability \( \left(\overline{S}(t)\right) \)	Predicted survival probability (Ŝ(t))	Ratio \( \left(\overline{S}(t)\right)/\left(\widehat{S}(t)\right) \)
≤ 15th (n = 59)	48 hours	0.91	0.95	0.96
≤ 15th (n = 59)	1 week	0.81	0.79	1.0
> 15th–50th (n = 70)	48 hours	0.88	0.89	1.0
> 15th–50th (n = 70)	1 week	0.62	0.60	1.0
> 50th –85th (n = 123)	48 hours	0.90	0.70	1.3
> 50th –85th (n = 123)	1 week	0.40	0.23	1.7
> 85th (n = 87)	48 hours	0.46	0.28	1.6
> 85th (n = 87)	1 week	0.14	0.02	7.0

ISSN: 1741-7015