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Table 3 Projected outcomes of six TB screening strategies for a cohort of 1000 healthcare workers over 20 years: alternate scenario with increased worker risk

From: Revisiting annual screening for latent tuberculosis infection in healthcare workers: a cost-effectiveness analysis

Strategy Cost in 2015 $CAN QALYs New active TB cases Deaths due to active TB Deaths due to adverse event to treatment of active TB Deaths due to adverse event to treatment of LTBI True positive results False positive results
Post-exposure screening only
 Tuberculin Skin Test $198,480 15,234.05 8.90 0.39 0.0068 0.00109 195 17
 QuantiFERON®-TB-Gold $228,809 15,233.75 8.73 0.38 0.0067 0.00119 201 30
Targeted screening
 Tuberculin Skin Test $257,670 15,232.84 8.18 0.36 0.0063 0.00152 193 96
 QuantiFERON®-TB-Gold $365,397 15,231.90 8.23 0.36 0.0063 0.00177 184 146
Annual screening
 Tuberculin Skin Test $487,837 15,227.38 7.64 0.33 0.0058 0.00307 203 373
 QuantiFERON®-TB-Gold $868,662 15,223.94 7.95 0.35 0.0061 0.00395 174 553
  1. TB tuberculosis, QALYs quality-adjusted life years, LTBI latent tuberculosis infection