Component of primary composite end-point | Pragmatic lifestyle modification n = 1726 | Control lifestyle modification n = 1813 | Incident rate ratio (95% confidence intervals) | P value |
---|---|---|---|---|
Composite | 479 | 561 | 0.89 (0.83–0.96) | 0.002 |
New onset T2DM | 58 | 72 | 0.8 (0.65–1.02) | 0.08 |
New onset IGT | 143 | 168 | 0.89 (0.79–1.01) | 0.08 |
New onset IFG | 146 | 166 | 0.93 (0.82–1.06) | 0.27 |
New onset dysglycaemiaa | 347 | 406 | 0.9 (0.83–0.97) | 0.013 |
Hypertension | 115 | 152 | 0.79 (0.68–0.9) | 0.01 |
Statin therapy | 41 | 46 | 0.92 (0.72–1.18) | 0.5 |
Renal disease events | 2 | 8 | 0.26 (0.1–0.63) | 0.003 |
Cardiovascular events | 1 | 0 | N/A | |
Deaths | 2 | 0 | N/A |