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Table 2 Effect of pragmatic lifestyle modification as compared to control lifestyle modification on the incidence of the primary cardio-metabolic composite endpoint and its individual components in 3539 healthy participants

From: A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: a randomised controlled trial

Component of primary composite end-point Pragmatic lifestyle modification n = 1726 Control lifestyle modification n = 1813 Incident rate ratio (95% confidence intervals) P value
Composite 479 561 0.89 (0.83–0.96) 0.002
New onset T2DM 58 72 0.8 (0.65–1.02) 0.08
New onset IGT 143 168 0.89 (0.79–1.01) 0.08
New onset IFG 146 166 0.93 (0.82–1.06) 0.27
New onset dysglycaemiaa 347 406 0.9 (0.83–0.97) 0.013
Hypertension 115 152 0.79 (0.68–0.9) 0.01
Statin therapy 41 46 0.92 (0.72–1.18) 0.5
Renal disease events 2 8 0.26 (0.1–0.63) 0.003
Cardiovascular events 1 0   N/A
Deaths 2 0   N/A
  1. aComposite of T2DM, IFG and IGT. T2DM type 2 diabetes mellitus, IGT impaired glucose tolerance, IFG impaired fasting glycaemia, N/A not applicable