|
Component of primary composite end-point
|
Pragmatic lifestyle modification n = 1726
|
Control lifestyle modification n = 1813
|
Incident rate ratio (95% confidence intervals)
|
P value
|
|---|
|
Composite
|
479
|
561
|
0.89 (0.83–0.96)
|
0.002
|
|
New onset T2DM
|
58
|
72
|
0.8 (0.65–1.02)
|
0.08
|
|
New onset IGT
|
143
|
168
|
0.89 (0.79–1.01)
|
0.08
|
|
New onset IFG
|
146
|
166
|
0.93 (0.82–1.06)
|
0.27
|
|
New onset dysglycaemiaa
|
347
|
406
|
0.9 (0.83–0.97)
|
0.013
|
|
Hypertension
|
115
|
152
|
0.79 (0.68–0.9)
|
0.01
|
|
Statin therapy
|
41
|
46
|
0.92 (0.72–1.18)
|
0.5
|
|
Renal disease events
|
2
|
8
|
0.26 (0.1–0.63)
|
0.003
|
|
Cardiovascular events
|
1
|
0
| |
N/A
|
|
Deaths
|
2
|
0
| |
N/A
|
-
aComposite of T2DM, IFG and IGT. T2DM type 2 diabetes mellitus, IGT impaired glucose tolerance, IFG impaired fasting glycaemia, N/A not applicable
