Table 2 Subject characteristics 6 years after index pregnancy by gestational hypertensive disorder (n = 3391)
From: Gestational hypertensive disorders and retinal microvasculature: the Generation R Study
Normotensive Pregnancy | GH | PE | P value | |
|---|---|---|---|---|
(n = 3183) | (n = 145) | (n = 63) | ||
Maternal characteristics (follow-up) | ||||
Age (years) | 36.7 (5.1) | 37.1 (4.9) | 36.0 (5.5) | 0.38 |
Visit interval (years) | 6.2 (5.7, 7.4) | 6.1 (5.7, 7.6) | 6.0 (5.7, 7.5) | 0.30 |
Systolic blood pressure (mmHg) | 118.1 (12.0) | 128.4 (17.6) | 126.5 (15.8) | <0.001 |
Diastolic blood pressure (mmHg) | 70.0 (9.3) | 78.2 (12.0) | 78.5 (12.4) | <0.001 |
Mean arterial pressure (mmHg) | 86.0 (9.6) | 95.0 (13.2) | 94.5 (12.9) | <0.001 |
Hypertension (no., %) | 203 (6.4) | 39 26.9) | 15 (23.8) | <0.001 |
Primigravid (no., %) | 225 (10.1) | 19 (17.0) | 9 (22.0) | 0.003 |
Medication (no., %) | ||||
Cholesterol-lowering medication | 8 (0.3) | 1 (0.7) | 0 (0.0) | 0.55 |
Glucose-lowering medication | 13 (0.4) | 2 (1.4) | 1 (1.6) | 0.11 |
Anti-hypertensives | 36 (1.1) | 10 (6.9) | 4 (6.3) | <0.001 |
Cardiovascular medication | 43 (1.4) | 10 (6.9) | 4 (6.3) | <0.001 |
Combined | 54 (1.7) | 11 (7.6) | 5 (7.9) | <0.001 |
Smoking (no., %) | 420 (18.9) | 21 (18.9) | 3 (7.3) | 0.17 |
Retinal arteriolar caliber (μm) | 145.8 (16.9) | 141.9 (17.8) | 137.8 (14.4) | <0.001 |
Retinal venular caliber (μm) | 207.1 (22.5) | 208.6 (22.5) | 203.8 (19.0) | 0.36 |
Retinal arteriolar venular ratio | 0.71 (0.07) | 0.68 (0.07) | 0.68 (0.06) | <0.001 |
Weight (kg) | 68.6 (53.6, 97.8) | 77.0 (58.8, 121.1) | 73.5 (53.3, 120.7) | <0.001 |
Body mass index (kg/m2) | 24.5 (19.7, 34.5) | 27.7 (21.3, 45.5) | 27.6 (19.6, 43.9) | <0.001 |