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Table 2 Subject characteristics 6 years after index pregnancy by gestational hypertensive disorder (n = 3391)

From: Gestational hypertensive disorders and retinal microvasculature: the Generation R Study

  Normotensive Pregnancy GH PE P value
  (n = 3183) (n = 145) (n = 63)  
Maternal characteristics (follow-up)
 Age (years) 36.7 (5.1) 37.1 (4.9) 36.0 (5.5) 0.38
 Visit interval (years) 6.2 (5.7, 7.4) 6.1 (5.7, 7.6) 6.0 (5.7, 7.5) 0.30
 Systolic blood pressure (mmHg) 118.1 (12.0) 128.4 (17.6) 126.5 (15.8) <0.001
 Diastolic blood pressure (mmHg) 70.0 (9.3) 78.2 (12.0) 78.5 (12.4) <0.001
 Mean arterial pressure (mmHg) 86.0 (9.6) 95.0 (13.2) 94.5 (12.9) <0.001
 Hypertension (no., %) 203 (6.4) 39 26.9) 15 (23.8) <0.001
 Primigravid (no., %) 225 (10.1) 19 (17.0) 9 (22.0) 0.003
 Medication (no., %)
  Cholesterol-lowering medication 8 (0.3) 1 (0.7) 0 (0.0) 0.55
  Glucose-lowering medication 13 (0.4) 2 (1.4) 1 (1.6) 0.11
  Anti-hypertensives 36 (1.1) 10 (6.9) 4 (6.3) <0.001
  Cardiovascular medication 43 (1.4) 10 (6.9) 4 (6.3) <0.001
  Combined 54 (1.7) 11 (7.6) 5 (7.9) <0.001
 Smoking (no., %) 420 (18.9) 21 (18.9) 3 (7.3) 0.17
 Retinal arteriolar caliber (μm) 145.8 (16.9) 141.9 (17.8) 137.8 (14.4) <0.001
 Retinal venular caliber (μm) 207.1 (22.5) 208.6 (22.5) 203.8 (19.0) 0.36
 Retinal arteriolar venular ratio 0.71 (0.07) 0.68 (0.07) 0.68 (0.06) <0.001
 Weight (kg) 68.6 (53.6, 97.8) 77.0 (58.8, 121.1) 73.5 (53.3, 120.7) <0.001
 Body mass index (kg/m2) 24.5 (19.7, 34.5) 27.7 (21.3, 45.5) 27.6 (19.6, 43.9) <0.001
  1. Values are percentages for categorical variables, means (SD) for continuous variables with a normal distribution, or medians (90% range) for continuous variables with a skewed distribution. Differences in baseline characteristics were tested using Student’s t test, ANOVA, Kruskal-Wallis, and chi-square tests. Values are not imputed