Baseline predictor variable
|
EMS
|
Spot
|
---|
OR
|
95% CI
|
P value
|
OR
|
95%
|
P value
|
---|
Baseline smear grading*
|
ZN Neg
|
0.63
|
0.18–2.11
|
0.45
|
–
|
–
|
–
|
ZN 1+
|
0.50
|
0.17–1.42
|
0.19
|
0.22
|
0.08–0.63
|
0.004
|
ZN 2+
|
0.38
|
0.17–0.87
|
0.02
|
0.82
|
0.48–1.39
|
0.46
|
ZN 3+
|
0.56
|
0.33–0.95
|
0.03
|
0.68
|
0.43–1.07
|
0.09
|
ZN 4+
|
Reference
|
Reference
|
Log10 LJ TTD
|
0.61
|
0.26–1.45
|
0.26
|
0.73
|
0.29–1.87
|
0.51
|
Log10 MGIT TTP
|
0.38
|
0.13–1.10
|
0.07
|
0.29
|
0.08–0.99
|
0.05
|
- *Unfavourable outcome is associated with increasing ZN smear for both EMS (P = 0.008) and spot (P = 0.002), non-parametric test for trend
-
CI confidence interval, EMS early morning sputum sample, LJ Lowenstein–Jensen, MGIT mycobacteria growth indicator tube, OR odds ratio, TTD time-to-detection, TTP time-to-positivity, ZN Ziehl–Neelsen