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Table 3 Costs and consequences for individual participants in a prevention programme

From: Economic evaluation of type 2 diabetes prevention programmes: Markov model of low- and high-intensity lifestyle programmes and metformin in participants with different categories of intermediate hyperglycaemia

Method of identifying participants Intervention Total cost (£,2015) Total QALYs Prevalence of T2DM after 50 years (%) Average number of years lived with T2DM after 50 years
IGT No intervention 17,772 11.53 42% 5.75
Pragmatic lifestyle programme 17,774 11.59 41% 5.43
Intensive lifestyle programme 18,423 11.76 33% 3.97
Metformin 17,988 11.60 38% 5.03
IFG No intervention 17,429 12.13 38% 5.34
Pragmatic lifestyle programme 17,440 12.19 37% 5.07
Intensive lifestyle programme 18,452 12.28 31% 3.98
Metformin 17,908 12.20 35% 4.68
HbA1c No intervention 17,436 12.13 38% 5.35
Pragmatic lifestyle programme 17,446 12.19 37% 5.08
Intensive lifestyle programme 18,507 12.27 31% 4.03
Metformin 17,475 12.23 33% 4.18
  1. Differences between costs and QALYs of ‘no intervention’ in the groups with IGT, IFG and HbA1c are due to: 1) higher hazard ratios of death with IGT relative to IFG/HbA1c, ii) lower baseline utilities for IGT relative to IFG/HbA1c and iii) higher baseline transition probabilities to T2DM with IGT relative to IFG/HbA1c, as outlined in Additional file 1: Appendix 1